Psychiatry Research: Neuroimaging
Volume 183, Issue 2 , Pages 174-176 , 30 August 2010

Thalamic neurochemical abnormalities in individuals with prodromal symptoms of schizophrenia — Relationship to auditory event-related potentials

  • James M. Stone

      Affiliations

    • Division of Experimental Medicine, Imperial College London, Burlington Danes Building, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
    • Department of Psychological Medicine and Psychiatry, King's College London, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 20 7848 0915; fax: +44 20 7848 0976.
    • ,
  • Elvira Bramon

      Affiliations

    • Department of Psychological Medicine and Psychiatry, King's College London, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    • ,
  • Astrid Pauls

      Affiliations

    • Department of Psychological Medicine and Psychiatry, King's College London, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    • ,
  • Alex Sumich

      Affiliations

    • Department of Psychological Medicine and Psychiatry, King's College London, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    • Division of Psychology, School of Social Sciences, Nottingham Trent University, Burton Street, Nottingham, NG1 4BU, UK
    • ,
  • Philip K. McGuire

      Affiliations

    • Department of Psychological Medicine and Psychiatry, King's College London, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK

Received 11 January 2010 ,Revised 20 March 2010 ,Accepted 13 May 2010.

References 

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  3. Bramon E, Shaikh M, Broome M, Lappin J, Berge D, Day F, et al. Abnormal P300 in people with high risk of developing psychosis. Neuroimage. 2008;41:553–560
  4. Frangou S, Sharma T, Alarcon G, Sigmudsson T, Takei N, Binnie C, et al. The Maudsley Family Study, II: Endogenous event-related potentials in familial schizophrenia. Schizophrenia Research. 1997;23:45–53
  5. Friedman D, Cycowicz YM, Gaeta H. The novelty P3: an event-related brain potential (ERP) sign of the brain's evaluation of novelty. Neuroscience & Biobehavioral Reviews. 2001;25:355–373
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  8. Phillips LJ, Yung AR, McGorry PD. Identification of young people at risk of psychosis: validation of Personal Assessment and Crisis Evaluation Clinic intake criteria. Australian and New Zealand Journal of Psychiatry. 2000;34(Suppl):S164–S169
  9. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magnetic Resonance in Medicine. 1993;30:672–679
  10. Semlitsch HV, Anderer P, Schuster P, Presslich O. A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERP. Psychophysiology. 1986;23:695–703
  11. Sharp FR, Tomitaka M, Bernaudin M, Tomitaka S. Psychosis: pathological activation of limbic thalamocortical circuits by psychomimetics and schizophrenia?. Trends in Neuroscience. 2001;24:330–334
  12. Stone JM, Morrison PD, Pilowsky LS. Glutamate and dopamine dysregulation in schizophrenia — a synthesis and selective review. Journal of Psychopharmacology. 2007;21:440–452
  13. Stone JM, Day F, Tsagaraki H, Valli I, McLean MA, Lythgoe DJ, et al. Glutamate dysfunction in people with prodromal symptoms of psychosis: relationship to gray matter volume. Biological Psychiatry. 2009;66:533–539
  14. Sumich A, Kumari V, Dodd P, Ettinger U, Hughes C, Zachariah E, et al. N100 and P300 amplitude to Go and No–Go variants of the auditory oddball in siblings discordant for schizophrenia. Schizophrenia Research. 2008;98:265–277
  15. Umbricht D, Schmid L, Koller R, Vollenweider FX, Hell D, Javitt DC. Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophrenia. Archives of General Psychiatry. 2000;57:1139–1147

PII: S0925-4927(10)00183-6

doi: 10.1016/j.pscychresns.2010.05.004

Psychiatry Research: Neuroimaging
Volume 183, Issue 2 , Pages 174-176 , 30 August 2010

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