Psychiatry Research: Neuroimaging
Volume 182, Issue 3 , Pages 261-265 , 30 June 2010

1H magnetic resonance spectroscopy imaging of the hippocampus in patients with panic disorder

  • Clarissa Trzesniak

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil
    • Corresponding Author InformationCorresponding author. Departamento de Neurociências e Ciências do Comportamento – FMRP-USP, Avenida Bandeirantes 3900, 14048-900 Ribeirão Preto, SP, Brazil. Tel.: +55 16 3602 2201; fax: +55 16 3602 2544.
  • ,
  • Ricardo R. Uchida

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • ,
  • David Araújo

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil
  • ,
  • Francisco S. Guimarães

      Affiliations

    • Department of Medical Clinic, Division of Pharmacology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • ,
  • Maria Cecília Freitas-Ferrari

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil
  • ,
  • Alaor Santos Filho

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil
  • ,
  • Antonio C. Santos

      Affiliations

    • Department of Medical Clinic, Division of Radiology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • ,
  • Geraldo F. Busatto

      Affiliations

    • Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil
  • ,
  • Antonio W. Zuardi

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil
  • ,
  • Cristina M. Del-Ben

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • ,
  • Frederico G. Graeff

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • ,
  • José A. Crippa

      Affiliations

    • Department of Neuroscience and Behavior, Division of Psychiatry, Faculty of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
    • INCT Translational Medicine, Brazil

Received 20 May 2009 ,Revised 11 March 2010 ,Accepted 16 March 2010.

References 

  1. Bartha R, Stein MB, Williamson PC, Drost DJ, Neufeld RW, Carr TJ, et al. A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive–compulsive disorder and comparison subjects. The American Journal of Psychiatry. 1998;155:1584–1591
  2. Bisaga A, Katz JL, Antonini A, Wright E, Margouleff C, Gorman JM, et al. Cerebral glucose metabolism in women with panic disorder. The American Journal of Psychiatry. 1998;155:1178–1183
  3. Bremner JD, Innis RB, White T, Fujita M, Silbersweig D, Goddard AW, et al. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry. 2000;47:96–106
  4. Burgess N, Maguire EA, O'Keefe J. The human hippocampus and spatial and episodic memory. Neuron. 2002;35:625–641
  5. Bystritsky A, Pontillo D, Powers M, Sabb FW, Craske MG, Bookheimer SY. Functional MRI changes during panic anticipation and imagery exposure. Neuroreport. 2001;12:3953–3957
  6. Dager SR, Marro KI, Richards TL, Metzger GD. Preliminary application of magnetic resonance spectroscopy to investigate lactate-induced panic. The American Journal of Psychiatry. 1994;151:57–63
  7. De Cristofaro MT, Sessarego A, Pupi A, Biondi F, Faravelli C. Brain perfusion abnormalities in drug-naive, lactate-sensitive panic patients: a SPECT study. Biological Psychiatry. 1993;3:505–512
  8. Deakin JWF, Graeff FG. 5-HT and mechanisms of defense. Journal of Psychopharmacology. 1991;5:305–315
  9. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders — Clinical Version (SCID-CV). Washington DC: American Psychiatric Press; 1997;
  10. Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OA, et al. Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Archives of General Psychiatry. 2001;58:556–561
  11. Goddard AW, Mason GF, Appel M, Rothman DL, Gueorguieva R, Behar KL, et al. Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder. The American Journal of Psychiatry. 2004;161:2186–2193
  12. Gorman JM, Kent JM, Sullivan GM, Coplan JD. Neuroanatomical hypothesis of panic disorder, revised. The American Journal of Psychiatry. 2000;157:493–505
  13. Grachev ID, Apkarian AV. Chemical mapping of anxiety in the brain of healthy humans: an in vivo 1H-MRS study on the effects of sex, age, and brain region. Human Brain Mapping. 2000;11:261–272
  14. Ham BJ, Sung Y, Kim N, Kim SJ, Kim JE, Kim DJ, et al. Decreased GABA levels in anterior cingulate and basal ganglia in medicated subjects with panic disorder: a proton magnetic resonance spectroscopy (1H-MRS) study. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2007;30:403–411
  15. Hasler G, Nugent AC, Carlson PJ, Carson RE, Geraci M, Drevets WC. Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography. Archives of General Psychiatry. 2008;65:1166–1175
  16. Hasler G, van der Veen JW, Geraci M, Shen J, Pine D, Drevets WC. Prefrontal cortical gamma-aminobutyric Acid levels in panic disorder determined by proton magnetic resonance spectroscopy. Biological Psychiatry. 2009;65:273–275
  17. Kim JJ, Fanselow MS. Modality-specific retrograde amnesia of fear. Science. 1992;256:675–677
  18. Klein DF, Gorman JM. A model of panic and agoraphobic development. Acta Psychiatrica Scandinavica Supplementum. 1987;335:87–95
  19. Klemenhagen KC, Gordon JA, David DJ, Hen R, Gross CT. Increased fear response to contextual cues in mice lacking the 5-HT1A receptor. Neuropsychopharmacology. 2006;31:101–111
  20. Kreis R. Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts. NMR in Biomedicine. 2004;17:361–381
  21. Layton ME, Friedman SD, Dager SR. Brain metabolic changes during lactate-induced panic: effects of gabapentin treatment. Depression and Anxiety. 2001;14:251–254
  22. Massana G, Gasto C, Junque C, Mercader JM, Gomez B, Massana J, et al. Reduced levels of creatine in the right medial temporal lobe region of panic disorder patients detected with (1)H magnetic resonance spectroscopy. Neuroimage. 2002;16:836–842
  23. Nordahl TE, Semple WE, Gross M, Mellman TA, Stein MB, Goyer P, et al. Cerebral glucose metabolic differences in patients with panic disorder. Neuropsychopharmacology. 1990;3:261–272
  24. Nordahl TE, Stein MB, Benkelfat C, Semple WE, Andreason P, Zametkin A, et al. Regional cerebral metabolic asymmetries replicated in an independent group of patients with panic disorders. Biological Psychiatry. 1998;44:998–1006
  25. Oldfield RC. The assessment and analysis of handedness: the Edinburg Inventory. Neuropsychologia. 1971;9:97–113
  26. Prasko J, Horacek J, Zalesky R, Kopecek M, Novak T, Paskova B, et al. The change of regional brain metabolism (18FDG PET) in panic disorder during the treatment with cognitive behavioral therapy or antidepressants. Neuroendocrinology Letters. 2004;25:340–348
  27. Sakai Y, Kumano H, Nishikawa M, Sakano Y, Kaiya H, Imabayashi E, et al. Cerebral glucose metabolism associated with a fear network in panic disorder. Neuroreport. 2005;16:927–931
  28. Sakai Y, Kumano H, Nishikawa M, Sakano Y, Kaiya H, Imabayashi E, et al. Changes in cerebral glucose utilization in patients with panic disorder treated with cognitive–behavioral therapy. Neuroimage. 2006;33:218–226
  29. Sanches RF, Crippa JA, Hallak JE, Araujo D, Zuardi AW. Proton magnetic resonance spectroscopy of the frontal lobe in schizophrenics: a critical review of the methodology. Revista do Hospital das Clínicas da Faculdade de Medicina de São Paulo. 2004;59:145–152
  30. Sanches RF, Crippa JA, Hallak JE, de Sousa JP, Araújo D, Santos AC, et al. Proton magnetic resonance spectroscopy of the frontal, cingulate and perirolandic cortices and its relationship to skin conductance in patients with schizophrenia. Brazilian Journal of Medical and Biological Research. 2008;41:1132–1141
  31. Trzesniak C, Araújo D, Crippa JAS. Magnetic resonance spectroscopy in anxiety disorders. Acta Neuropsychiatrica. 2008;20:56–71
  32. Tsetsenis T, Ma XH, Lo Iacono L, Beck SG, Gross C. Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus. Nature Neuroscience. 2007;10:896–902
  33. Uchida RR, Del-Ben CM, Santos AC, Araújo D, Crippa JAS, Guimarães FS, et al. Decreased left temporal lobe volume of panic patients measured by magnetic resonance imaging. Brazilian Journal of Medical and Biological Research. 2003;36:925–929
  34. Yildiz-Yesiloglu A, Ankerst DP. Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: a meta-analysis. Psychiatry Research: Neuroimaging. 2006;147:1–25

PII: S0925-4927(10)00110-1

doi: 10.1016/j.pscychresns.2010.03.008

Psychiatry Research: Neuroimaging
Volume 182, Issue 3 , Pages 261-265 , 30 June 2010