Psychiatry Research: Neuroimaging
Volume 182, Issue 3 , Pages 244-250 , 30 June 2010

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease

  • Stefan J. Teipel

      Affiliations

    • Department of Psychiatry, University Rostock, Germany
    • Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Germany
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, University of Rostock, Gehlsheimer Str. 20, 18147 Rostock, Germany. Tel.: +49 381 494 9610; fax: +49 381 494 9682.
  • ,
  • Michael Ewers

      Affiliations

    • Department of Psychiatry, Ludwig-Maximilian University Munich, Germany
    • Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Ireland
  • ,
  • Stefanie Wolf

      Affiliations

    • Department of Psychiatry, University Göttingen, Germany
  • ,
  • Frank Jessen

      Affiliations

    • Department of Psychiatry, University Bonn, Germany
  • ,
  • Heike Kölsch

      Affiliations

    • Department of Psychiatry, University Bonn, Germany
  • ,
  • Sönke Arlt

      Affiliations

    • Department of Psychiatry, University of Hamburg, Germany
  • ,
  • Christian Luckhaus

      Affiliations

    • Department of Psychiatry, University of Düsseldorf, Germany
  • ,
  • Peter Schönknecht

      Affiliations

    • Department of Psychiatry, University of Heidelberg, Germany
    • Department of Psychiatry, University of Leipzig, Germany
  • ,
  • Klaus Schmidtke

      Affiliations

    • Department of Psychiatry, University of Freiburg, Germany
  • ,
  • Isabella Heuser

      Affiliations

    • Department of Psychiatry, Charité-University Medicine Berlin, Germany
  • ,
  • Lutz Frölich

      Affiliations

    • Central Institute of Mental Health, Mannheim, Germany
  • ,
  • Gabriele Ende

      Affiliations

    • Central Institute of Mental Health, Mannheim, Germany
  • ,
  • Johannes Pantel

      Affiliations

    • Department of Psychiatry, University of Frankfurt, Germany
  • ,
  • Jens Wiltfang

      Affiliations

    • Department of Psychiatry, University of Essen, Germany
  • ,
  • Fabian Rakebrandt

      Affiliations

    • Department of Medical Informatics, Georg August University, Göttingen, Germany
  • ,
  • Oliver Peters

      Affiliations

    • Department of Psychiatry, Charité-University Medicine Berlin, Germany
  • ,
  • Christine Born

      Affiliations

    • Department of Clinical Radiology, Ludwig-Maximilian University, Munich, Germany
  • ,
  • Johannes Kornhuber

      Affiliations

    • Department of Psychiatry, University of Erlangen, Erlangen, Germany
  • ,
  • Harald Hampel

      Affiliations

    • Department of Psychiatry, Ludwig-Maximilian University Munich, Germany
    • Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Ireland

Received 12 January 2009 ,Revised 16 February 2010 ,Accepted 11 March 2010.

References 

  1. ACR . In:  Reston V editors. Phantom Test Guidance for the ACR MRI Accreditation Program. American College of Radiology; 2000;
  2. Apostolova LG, Dinov ID, Dutton RA, Hayashi KM, Toga AW, Cummings JL, et al. 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease. Brain. 2006;129(Pt 11):2867–2873
  3. Basso M, Gelernter J, Yang J, MacAvoy MG, Varma P, Bronen RA, et al. Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease. Neurobiology of Aging. 2006;27(10):1416–1424
  4. Basso M, Yang J, Warren L, MacAvoy MG, Varma P, Bronen RA, et al. Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease. Psychiatry Research: Neuroimaging. 2006;146(3):251–261
  5. Bottino CM, Castro CC, Gomes RL, Buchpiguel CA, Marchetti RL, Neto MR. Volumetric MRI measurements can differentiate Alzheimer's disease, mild cognitive impairment, and normal aging. International Psychogeriatrics. 2002;14(1):59–72
  6. Brown H, Prescott R. Applied Mixed Models in Medicine. Chichester, UK: John Wiley & Sons Ltd; 1999;
  7. Chetelat G, Baron JC. Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging. Neuroimage. 2003;18(2):525–541
  8. Cohen J. Statistical Power Analysis for the Behavioural Sciences. New York: Academic Press; 1977;
  9. Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. Journal of Computer Assisted Tomography. 1994;18(2):192–205
  10. Devanand DP, Pradhaban G, Liu X, Khandji A, De Santi S, Segal S, et al. Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology. 2007;68(11):828–836
  11. Erdfelder E, Faul F, Buchner A. GPOWER: a general power analysis program. Behavior Research Methods, Instruments & Computers. 1996;28:1–11
  12. Ewers M, Teipel SJ, Dietrich O, Schonberg SO, Jessen F, Heun R, et al. Multicenter assessment of reliability of cranial MRI. Neurobiology of Aging. 2006;27(8):1051–1059
  13. Farlow MR, He Y, Tekin S, Xu J, Lane R, Charles HC. Impact of APOE in mild cognitive impairment. Neurology. 2004;63(10):1898–1901
  14. Fleisher A, Grundman M, Jack CR, Petersen RC, Taylor C, Kim HT, et al. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Archives of Neurolology. 2005;62(6):953–957
  15. Folstein MF, Folstein SE, McHugh PR. Mini-mental-state: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research. 1975;12189–12198
  16. Goldstein H. Multilevel Statistical Models. 2nd ed. London: Edward Arnold; 1995;
  17. Golebiowski M, Barcikowska M, Pfeffer A. Magnetic resonance imaging-based hippocampal volumetry in patients with dementia of the Alzheimer type. Dementia and Geriatric Cognitive Disorders. 1999;10(4):284–288
  18. Hamalainen A, Grau-Olivares M, Tervo S, Niskanen E, Pennanen C, Huuskonen J, et al. Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxel-based morphometric study. Neurodegenerative Diseases. 2008;5(3–4):186–189
  19. Hampel H, Teipel SJ, Bayer W, Alexander GE, Schwarz R, Schapiro MB, et al. Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease. Journal of the Neurological Sciences. 2002;194(1):15–19
  20. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;14329–14336
  21. Hashimoto M, Yasuda M, Tanimukai S, Matsui M, Hirono N, Kazui H, et al. Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease. Neurology. 2001;57(8):1461–1466
  22. Jack CR, Petersen RC, Xu YC, Waring SC, O'Brien PC, Tangalos EG, et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology. 1997;49:786–794
  23. Jack CR, Petersen RC, Xu YC, O'Brien PC, Waring SC, Tangalos EG, et al. Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Annals of Neurololgy. 1998;43(3):303–310
  24. Killiany RJ, Gomez-Isla T, Moss M, Kikinis R, Sandor T, Jolesz F, et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Annals of Neurology. 2000;47(4):430–439
  25. Kohler S, Black SE, Sinden M, Szekely C, Kidron D, Parker JL, et al. Memory impairments associated with hippocampal versus parahippocampal-gyrus atrophy: an MR volumetry study in Alzheimer's disease. Neuropsychologia. 1998;36(9):901–914
  26. Kramer JH, Schuff N, Reed BR, Mungas D, Du AT, Rosen HJ, et al. Hippocampal volume and retention in Alzheimer's disease. Journal of the International Neuropsychology Society. 2004;10(4):639–643
  27. Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics. 1982;38(4):963–974
  28. Lehtovirta M, Soininen H, Laakso MP, Partanen K, Helisalmi S, Mannermaa A, et al. SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele. Journal of Neurology, Neurosurgery, and Psychiatry. 1996;60(6):644–649
  29. Littell RC, Milliken GA, Stroup WW, Wolfinger RD. SAS System for Mixed Models. Cary, NC, USA: SAS Institute Inc; 1996;
  30. Lopez OL, Kuller LH, Becker JT, Dulberg C, Sweet RA, Gach HM, et al. Incidence of dementia in mild cognitive impairment in the cardiovascular health study cognition study. Archives of Neurology. 2007;64(3):416–420
  31. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 1984;34:939–944
  32. Mizuno K, Wakai M, Takeda A, Sobue G. Medial temporal atrophy and memory impairment in early stage of Alzheimer's disease: an MRI volumetric and memory assessment study. Journal of the Neurological Sciences. 2000;173(1):18–24
  33. Moore PM, Baker GA. Validation of the Wechsler Memory Scale-Revised in a sample of people with intractable temporal lobe epilepsy. Epilepsia. 1996;37(12):1215–1220
  34. Mori E, Yoneda Y, Yamashita H, Hirono N, Ikeda M, Yamadori A. Medial temporal structures relate to memory impairment in Alzheimer's disease: an MRI volumetric study. Journal of Neurology, Neurosurgery, and Psychiatry. 1997;63(2):214–221
  35. Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology. 1993;43(11):2412–2414
  36. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology. 1989;39(9):1159–1165
  37. Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hanninen T, Laakso MP, et al. Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiology of Aging. 2004;25(3):303–310
  38. Petersen RC, Jack CR, Xu YC, Waring SC, O'Brien PC, Smith GE, et al. Memory and MRI-based hippocampal volumes in aging and AD. Neurology. 2000;54(3):581–587
  39. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, et al. Current concepts in mild cognitive impairment. Archives of Neurology. 2001;58(12):1985–1992
  40. Pruessner JC, Li LM, Serles W, Pruessner M, Collins DL, Kabani N, et al. Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories. Cerebral Cortex. 2000;10(4):433–442
  41. Pruessner JC, Collins DL, Pruessner M, Evans AC. Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood. Journal of Neuroscience. 2001;21(1):194–200
  42. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. American Journal of Psychiatry. 1984;1411356–1411364
  43. Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Transactions on Medical Imaging. 1998;17(1):87–97
  44. Squire LR. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychological Review. 1992;99195–99231
  45. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. New York: Thieme; 1988;
  46. Teipel SJ, Pruessner JC, Faltraco F, Born C, Rocha-Unold M, Evans A, et al. Comprehensive dissection of the medial temporal lobe in AD: measurement of hippocampus, amygdala, entorhinal, perirhinal and parahippocampal cortices using MRI. Journal of Neurology. 2006;253(6):794–800
  47. Teipel SJ, Mitchell A, Möller H-J, Hampel H. Improving linear modeling of cognitive decline in patients with mild cognitive impairment: comparison of two methods. Journal of Neural Transmission Supplement Suppl. 2007;72241–72247
  48. Wechsler D. A standardized memory scale for clinical use. Journal of Psychology. 1945;19:87–95

PII: S0925-4927(10)00104-6

doi: 10.1016/j.pscychresns.2010.03.003

Psychiatry Research: Neuroimaging
Volume 182, Issue 3 , Pages 244-250 , 30 June 2010