Superior temporal gyrus volume in teenagers with first-presentation borderline personality disorder

Takahashi, Tsutomu; Chanen, Andrew M.; Wood, Stephen J.; Yücel, Murat; Kawasaki, Yasuhiro; McGorry, Patrick D.; Suzuki, Michio; Velakoulis, Dennis; Pantelis, Christos

doi:10.1016/j.pscychresns.2009.10.014

« Previous Next »Psychiatry Research: Neuroimaging
Volume 182, Issue 1 , Pages 73-76, 30 April 2010

Superior temporal gyrus volume in teenagers with first-presentation borderline personality disorder

Tsutomu Takahashi
- Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
- Department of Neuropsychiatry, The University of Toyama, Toyama, Japan
- Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Tokyo, Japan
- Corresponding author. Melbourne Neuropsychiatry Centre, c/o National Neuroscience Facility, 161 Barry Street, Carlton South, Victoria 3053, Australia. Tel.: +61 3 8344 1800; fax: +61 3 9348 0469.
Andrew M. Chanen
- Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia
- Orygen Youth Health Clinical Program, Northwestern Mental Health, Melbourne, Australia
Stephen J. Wood
- Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Murat Yücel
- Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
- Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia
Yasuhiro Kawasaki
- Department of Neuropsychiatry, The University of Toyama, Toyama, Japan
- Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Tokyo, Japan
Patrick D. McGorry
- Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia
- Orygen Youth Health Clinical Program, Northwestern Mental Health, Melbourne, Australia
Michio Suzuki
- Department of Neuropsychiatry, The University of Toyama, Toyama, Japan
- Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Tokyo, Japan
Dennis Velakoulis
- Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Christos Pantelis
- Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia

Received 19 June 2009; received in revised form 27 October 2009; accepted 29 October 2009.

Abstract

This magnetic resonance imaging study investigated the superior temporal gyrus (STG) subregion volumes in 20 teenagers with first-presentation borderline personality disorder (BPD) and 20 healthy controls. While the STG volume early in the course of BPD did not differ from that of healthy controls, the BPD participants with violent episodes had a smaller left caudal STG volume compared with those without such episodes during the previous 6months. Our preliminary findings might reflect the neurobiological heterogeneity of the disorder.