Psychiatry Research: Neuroimaging
Volume 181, Issue 2 , Pages 151-154 , 28 February 2010

Reduced interhemispheric structural connectivity between anterior cingulate cortices in borderline personality disorder

  • Nicolas Rüsch

      Affiliations

    • Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany. Tel.: +49 761 270 6501; fax: +49 761 270 6619.
    • ,
  • Tobias Bracht

      Affiliations

    • Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    • ,
  • Björn W. Kreher

      Affiliations

    • Department of Diagnostic Radiology, Medical Physics, University of Freiburg, Germany
    • ,
  • Susanne Schnell

      Affiliations

    • Department of Diagnostic Radiology, Medical Physics, University of Freiburg, Germany
    • ,
  • Volkmar Glauche

      Affiliations

    • Department of Neurology, University of Freiburg, Germany
    • ,
  • Kamil A. Il'yasov

      Affiliations

    • Department of Diagnostic Radiology, Medical Physics, University of Freiburg, Germany
    • ,
  • Dieter Ebert

      Affiliations

    • Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    • ,
  • Klaus Lieb

      Affiliations

    • Department of Psychiatry, University of Mainz, Germany
    • ,
  • Jürgen Hennig

      Affiliations

    • Department of Diagnostic Radiology, Medical Physics, University of Freiburg, Germany
    • ,
  • Dorothee Saur

      Affiliations

    • Department of Neurology, University of Freiburg, Germany
    • The last two authors contributed equally.
    • ,
  • Ludger Tebartz van Elst

      Affiliations

    • Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    • The last two authors contributed equally.

Received 12 November 2008 ,Revised 14 June 2009 ,Accepted 28 August 2009.

References 

  1. Arnone D, Barrick TR, Chengappa S, Mackay CE, Clark CA, Abou-Saleh MT. Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics. NeuroImage. 2008;41:1067–1074
  2. Ashburner J, Friston KJ. Unified segmentation. NeuroImage. 2005;26:839–851
  3. Banich MT. The missing link: the role of interhemispheric interaction in attentional processing. Brain and Cognition. 1998;36:128–157
  4. Beaulieu C. The basis of anisotropic water diffusion in the nervous system — a technical review. NMR in Biomedicine. 2002;15:435–455
  5. Bracht, T., Tüscher, O., Schnell, S., Kreher, B.W., Rüsch, N., Glauche, V., Lieb, K., Ebert, D., Il'yasov, K.A., Hennig, J., Weiller, C., Tebartz van Elst, L., Saur, D., 2009. Extraction of prefronto-amygdalar pathways by combining probability maps. Psychiatry Research Neuroimaging 174, 217–222.
  6. Davids E, Gastpar M. Attention deficit hyperactivity disorder and borderline personality disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2005;29:865–877
  7. Davidson RJ, Putnam KM, Larson CL. Dysfunction in the neural circuitry of emotion regulation — a possible prelude to violence. Science. 2000;289:591–594
  8. Fan J, Hof PR, Guise KG, Fossella JA, Posner MI. The functional integration of the anterior cingulate cortex during conflict processing. Cerebral Cortex. 2008;18:796–805
  9. Fossati A, Novella L, Donati D, Donini M, Maffei C. History of childhood attention deficit/hyperactivity disorder symptoms and borderline personality disorder: a controlled study. Comprehensive Psychiatry. 2002;43:369–377
  10. Hazlett EA, New AS, Newmark R, Haznedar MM, Lo JN, Speiser LJ, et al. Reduced anterior and posterior cingulate gray matter in borderline personality disorder. Biological Psychiatry. 2005;58:614–623
  11. Kreher BW, Schnell S, Mader I, Il'yasov KA, Hennig J, Kiselev VG, et al. Connecting and merging fibres: pathway extraction by combining probability maps. NeuroImage. 2008;43:81–89
  12. Lehrl S. Mehrfachwahl-Wortschatz-Intelligenztest MWT-B. 5 edn.. Balingen: Spitta; 2005;
  13. Lehrl S, Triebig G, Fischer B. Multiple choice vocabulary test MWT as a valid and short test to estimate premorbid intelligence. Acta Neurologica Scandinavica. 1995;91:335–345
  14. Makris N, Biederman J, Monuteaux MC, Seidman LJ. Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorder. Developmental Neuroscience. 2009;31:36–49
  15. Margulies DS, Kelly AM, Uddin LQ, Biswal BB, Castellanos FX, Milham MP. Mapping the functional connectivity of anterior cingulate cortex. NeuroImage. 2007;37:579–588
  16. Mériau K, Wartenburger I, Kazzer P, Prehn K, Lammers CH, van der Meer E, et al. A neural network reflecting individual differences in cognitive processing of emotions during perceptual decision making. NeuroImage. 2006;33:1016–1027
  17. Minzenberg MJ, Fan J, New AS, Tang CY, Siever LJ. Fronto-limbic dysfunction in response to facial emotion in borderline personality disorder: an event-related fMRI study. Psychiatry Research. 2007;155:231–243
  18. Minzenberg MJ, Fan J, New AS, Tang CY, Siever LJ. Frontolimbic structural changes in borderline personality disorder. Journal of Psychiatric Research. 2008;42:727–733
  19. Rüsch, N., Boeker, M., Büchert, M., Glauche, V., Bohrmann, C., Ebert, D., Lieb, K., Hennig, J., Tebartz van Elst, L., 2008. Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder. World Journal of Biological Psychiatry (epublication 12 March). doi:10.1080/15622970801958331.
  20. Rüsch N, Luders E, Lieb K, Zahn R, Ebert D, Thompson PM, et al. Corpus callosum abnormalities in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder. Journal of Psychiatry & Neuroscience. 2007;32:417–422
  21. Rüsch N, Weber M, Il'yasov K, Lieb K, Ebert D, Hennig J, et al. Inferior frontal white matter microstructure and patterns of psychopathology in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder. NeuroImage. 2007;35:738–747
  22. Schmahl C, Bremner JD. Neuroimaging in borderline personality disorder. Journal of Psychiatric Research. 2006;40:419–427
  23. Schmahl C, Bohus M, Esposito F, Treede RD, Di Salle F, Greffrath W, et al. Neural correlates of antinociception in borderline personality disorder. Archives of General Psychiatry. 2006;63:659–667
  24. Seidman LJ, Valera EM, Makris N, Monuteaux MC, Boriel DL, Kelkar K, et al. Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging. Biological Psychiatry. 2006;60:1071–1080
  25. Silbersweig D, Clarkin JF, Goldstein M, Kernberg OF, Tüscher O, Levy KN, et al. Failure of frontolimbic inhibitory function in the context of negative emotion in borderline personality disorder. American Journal of Psychiatry. 2007;164:1832–1841
  26. Soloff P, Nutche J, Goradia D, Diwadkar V. Structural brain abnormalities in borderline personality disorder: a voxel-based morphometry study. Psychiatry Research Neuroimaging. 2008;164:223–236
  27. Tebartz van Elst L, Hesslinger B, Thiel T, Geiger E, Haegele K, Lemieux L, et al. Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study. Biological Psychiatry. 2003;54:163–171
  28. Tian L, Jiang T, Wang Y, Zang Y, He Y, Liang M, et al. Altered resting-state functional connectivity patterns of anterior cingulate cortex in adolescents with attention deficit hyperactivity disorder. Neuroscience Letters. 2006;400:39–43
  29. Whittle S, Chanen AM, Fornito A, McGorry PD, Pantelis C, Yucel M. Anterior cingulate volume in adolescents with first-presentation borderline personality disorder. Psychiatry Research: Neuroimaging. 2009;172:155–160
  30. Williams LM, Sidis A, Gordon E, Meares RA. “Missing links” in borderline personality disorder: loss of neural synchrony relates to lack of emotion regulation and impulse control. Journal of Psychiatry & Neuroscience. 2006;31:181–188

PII: S0925-4927(09)00194-2

doi: 10.1016/j.pscychresns.2009.08.004

Psychiatry Research: Neuroimaging
Volume 181, Issue 2 , Pages 151-154 , 28 February 2010

Article Tools

* Image Usage & Resolution