Psychiatry Research: Neuroimaging
Volume 174, Issue 1 , Pages 57-61 , 30 October 2009

Corpus callosum volume in children with autism

  • Antonio Y. Hardan

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
    • Corresponding Author InformationCorresponding author. 401 Quarry Road, Stanford, CA 94305, USA. Tel.: +1 650 723 5511; fax: +1 650 724 7389.
  • ,
  • Melissa Pabalan

      Affiliations

    • Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA
  • ,
  • Nidhi Gupta

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
  • ,
  • Rahul Bansal

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA
  • ,
  • Nadine M. Melhem

      Affiliations

    • Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA
  • ,
  • Serguei Fedorov

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA
  • ,
  • Matcheri S. Keshavan

      Affiliations

    • Department of Psychiatry, Beth Israel and Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
  • ,
  • Nancy J. Minshew

      Affiliations

    • Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA

Received 14 April 2008 ,Revised 22 November 2008 ,Accepted 16 March 2009.

References 

  1. Alexander AL, Lee JE, Lazar M, Boudos R, Dubray MB, Oakes TR, et al. Diffusion tensor imaging of the corpus callosum in Autism. Neuroimage. 2007;34:61–73
  2. American Psychiatric Association . Diagnostic and statistical manual of mental disorders. In: American Psychiatric Association 4th edition (DSM-IV-TR). Washington, DC: American Psychiatric Press; 2000;
  3. Badaruddin DH, Andrews GL, Bolte S, Schilmoeller KJ, Schilmoeller G, Paul LK, et al. Social and behavioral problems of children with agenesis of the corpus callosum. Child Psychiatry and Human Development. 2007;38:287–302
  4. Barnea-Goraly N, Kwon H, Menon V, Eliez S, Lotspeich L, Reiss AL. White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biological Psychiatry. 2004;55:323–326
  5. Boger-Megiddo I, Shaw DW, Friedman SD, Sparks BF, Artru AA, Giedd JN, et al. Corpus callosum morphometrics in young children with autism spectrum disorder. Journal of Autism and Developmental Disorders. 2006;36:733–739
  6. Brambilla P, Hardan AY, Ucelli di Nemi S, Perez J, Soares JC, Barale F. Brain anatomy and development in autism: review of structural MRI studies. Brain Research Bulletin. 2003;61:557–569
  7. Chung MK, Dalton KM, Alexander AL, Davidson RJ. Less white matter concentration in autism: 2D voxel-based morphometry. Neuroimage. 2004;23:242–251
  8. Clarke JM, Zaidel E. Anatomical-behavioral relationships: corpus callosum morphometry and hemispheric specialization. Behavioural Brain Research. 1994;64:185–202
  9. Doherty D, Tu S, Schilmoeller K, Schilmoeller G. Health-related issues in individuals with agenesis of the corpus callosum. Child Care Health and Development. 2006;32:333–342
  10. Dunn W. Performance of typical children on the sensory profile: an item analysis. American Journal of Occupational Therapy. 1994;48:967–974
  11. Dunn W. Sensory Profile. San Antonio, TX: Psychological Corporation; 1999;
  12. Egaas B, Courchesne E, Saitoh O. Reduced size of the corpus callosum in autism. Archives of Neurology. 1995;52:794–801
  13. Elia M, Ferri R, Musumeci SA, Panerai S, Bottitta M, Scuderi C. Clinical correlates of brain morphometric features of subjects with low-functioning autistic disorder. Journal of Child Neurology. 2000;15:504–508
  14. Farchione TR, Lorch E, Rosenberg DR. Hypoplasia of the corpus callosum and obsessive–compulsive symptoms. Journal of Child Neurology. 2002;17:535–537
  15. Feise RJ. Do multiple outcome measures require P-value adjustment?. BMC Medical Research Methodology. 2002;2:8
  16. Filipek PA. Brief report: neuroimaging in autism: the state of the science 1995. Journal of Autism and Developmental Disorders. 1996;26:211–215
  17. Gaffney GR, Tsai LY, Kuperman S, Minchin S. Cerebellar structure in autism. American Journal of Diseases of Children. 1987;141:1330–1332
  18. Hardan AY, Minshew NJ, Keshavan MS. Corpus callosum size in autism. Neurology. 2000;55:1033–1036
  19. Hazlett EA, Buchsbaum MS, Hsieh P, Haznedar MM, Platholi J, LiCalzi EM, et al. Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients. Neuropsychobiology. 2004;49:115–125
  20. Haznedar MM, Buchsbaum MS, Metzger M, Solimando A, Spiegel-Cohen J, Hollander E. Anterior cingulate gyrus volume and glucose metabolism in autistic disorder. American Journal of Psychiatry. 1997;154:1047–1050
  21. Herbert MR, Ziegler DA, Makris N, Filipek PA, Kemper TL, Normandin JJ, et al. Localization of white matter volum increase in autism and developmental language disorder. Annals of Neurology. 2004;55:530–540
  22. Hofer S, Frahm J. Topography of the human corpus callosum revisited-comprehensive fiber tractography using diffusion tensor magnetic resonance imaging. Neuroimage. 2006;32:989–994
  23. Hollingshead AB. Four Factor Index of Social Status. New Haven, CT: Yale University Department of Sociology; 1975;
  24. Huang H, Zhang J, Jiang H, Wakana S, Poetscher L, Miller MI, et al. DTI tractography based parcellation of white matter: application to the mid-sagittal morphology of corpus callosum. Neuroimage. 2005;26:195–205
  25. Jancke L, Staiger JF, Schlaug G, Huang Y, Steinmetz H. The relationship between corpus callosum size and forebrain volume. Cerebral Cortex. 1997;7:48–56
  26. Jancke L, Preis S, Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport. 1999;10:2981–2985
  27. Just MA, Cherkassky VL, Keller TA, Minshew NJ. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain. 2004;127:1811–1821
  28. Korkmaz B, Benbir G, Demirbilek V. Migration abnormality in the left cingulate gyrus presenting with autistic disorder. Journal of Child Neurology. 2006;21:600–604
  29. LaMantia AS, Rakic P. Axon overproduction and elimination in the corpus callosum of the developing rhesus monkey. Journal of Neuroscience. 1990;10:2156–2175
  30. Lord C, Rutter M, Goode S, Heemsbergen J, Jordan H, Mawhood L, et al. Autism diagnostic observation schedule: a standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders. 1989;19:185–212
  31. Lord C, Rutter M, Le Couteur A. Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders. 1994;24:659–685
  32. Magnotta VA, Harris G, Andreasen NC, O'Leary DS, Yuh WT, Heckel D. Structural MR image processing using the BRAINS2 toolbox. Computerized Medical Imaging and Graphics. 2002;26:251–264
  33. Manes F, Piven J, Vrancic D, Nanclares V, Plebst C, Starkstein SE. An MRI study of the corpus callosum and cerebellum, in mentally retarded autistic individuals. Journal of Neuropsychiatry and Clinical Neurosciences. 1999;11:470–474
  34. Minshew NJ, Williams DL. The new neurobiology of autism: cortex, connectivity, and neuronal organization. Archives of Neurology. 2007;64:945–950
  35. Narberhaus A, Segarra D, Caldú X, Giménez M, Pueyo R, Botet F, et al. Corpus callosum and prefrontal functions in adolescents with history of very preterm birth. Neuropsychologia. 2008;15:111–116
  36. Paul LK, Schieffer B, Brown WS. Social processing deficits in agenesis of the corpus callosum: narratives from the thematic appreciation test. Archives of Clinical Neuropsychology. 2004;19:215–225
  37. Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, et al. Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nature Reviews. Neuroscience. 2007;8:287–299
  38. Piven J, Bailey J, Ranson BJ, Arndt S. An MRI study of the corpus callosum in autism. American Journal of Psychiatry. 1997;154:1051–1056
  39. Plessen KJ, Wentzel-Larsen T, Hugdahl K, Feineigle P, Klein J, Staib LH, et al. Altered interhemispheric connectivity in individuals with Tourette's disorder. American Journal of Psychiatry. 2004;161:2028–2037
  40. Rapin I, Katzman R. Neurobiology of autism. Annals of Neurology. 1998;43:7–14
  41. Rosenberg DR, Keshavan MS, Dick EL, Bagwell WW, MacMaster FP, Birmaher B. Corpus callosal morphology in treatment-naive pediatric obsessive compulsive disorder. Progress in Neuro-psychopharmacology & Biological Psychiatry. 1997;21:1269–1283
  42. Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology. 1990;1:43–46
  43. Sanchez MM, Hearn EF, Do D, Rilling JK, Herndon JG. Differential rearing affects corpus callosum size and cognitive function of rhesus monkeys. Brain Research. 1998;812:38–49
  44. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York: Thieme; 1988;
  45. Thompson PM, Giedd JN, Woods RP, MacDonald D, Evans AC, Toga AW. Growth patterns in the developing brain detected by using continuum mechanical tensor maps. Nature. 2000;9:190–193
  46. Vidal CN, Nicolson R, DeVito TJ, Hayashi KM, Geaga JA, Drost DJ, et al. Mapping corpus callosum deficits in autism: an index of aberrant cortical connectivity. Biological Psychiatry. 2006;60:218–225
  47. White T, Andreasen NC, Nopoulos P, Magnotta V. Gyrification abnormalities in childhood- and adolescent-onset schizophrenia. Biological Psychiatry. 2003;54:418–426
  48. Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. Brain. 1989;112:799–835
  49. Wood AG, Saling MM, Jackson GD, Reutens DC. Asymmetry of language activation relates to regional callosal morphology following early cerebral injury. Epilepsy & Behavior. 2008;12:427–433

PII: S0925-4927(09)00086-9

doi: 10.1016/j.pscychresns.2009.03.005

Psychiatry Research: Neuroimaging
Volume 174, Issue 1 , Pages 57-61 , 30 October 2009