Psychiatry Research: Neuroimaging
Volume 173, Issue 3 , Pages 170-176 , 30 September 2009

Brain activation during executive processes in schizophrenia

  • Aurélie Royer

      Affiliations

    • Department of Psychiatry, University Hospital of Bellevue, Saint-Etienne, France
    • Corresponding Author InformationCorresponding author. Pavillon 52B de Psychiatrie Adulte, CHU Hôpital Bellevue, 42055 Saint-Etienne Cedex 2, France. Tel.: +33 4 77 12 76 57; fax: +33 4 77 12 03 87.
  • ,
  • Fabien Christian Georges Schneider

      Affiliations

    • Department of Radiology, University Hospital of Bellevue, Saint-Etienne, France
  • ,
  • Anne Grosselin

      Affiliations

    • Department of Psychiatry, University Hospital of Bellevue, Saint-Etienne, France
  • ,
  • Jacques Pellet

      Affiliations

    • Department of Psychiatry, University Hospital of Bellevue, Saint-Etienne, France
  • ,
  • Fabrice-Guy Barral

      Affiliations

    • Department of Radiology, University Hospital of Bellevue, Saint-Etienne, France
  • ,
  • Bernard Laurent

      Affiliations

    • Department of Neurology, University Hospital of Bellevue, Saint-Etienne, France
  • ,
  • Denis Brouillet

      Affiliations

    • LaMeCo, University of Montpellier III, France
  • ,
  • François Lang

      Affiliations

    • Department of Psychiatry, University Hospital of Bellevue, Saint-Etienne, France

Received 20 July 2007 ,Revised 15 January 2009 ,Accepted 23 February 2009.

References 

  1. Barch DM, Carter CS, Perlstein W, Baird J, Cohen JD, Schooler N. Increased Stroop facilitation effects in schizophrenia are not due to increased automatic spreading activation. Schizophrenia Bulletin. 1999;39:51–64
  2. Barch DM, Carter CS, Braver TS, Sabb FW, McDonald A, Noll DC, et al. Selective deficits in prefrontal cortex function in medication-naïve patients with schizophrenia. Archives of General Psychiatry. 2001;58:280–288
  3. Barch DM, Sheline YI, Csernansky JG, Snyder AZ. Working memory and prefrontal cortex dysfunction: specificity to schizophrenia compared with major depression. Biological Psychiatry. 2003;53:376–384
  4. Britton PG, Savage RD. A short form of the WAIS for used with the aged. British Journal of Psychiatry. 1966;112:417–418
  5. Bullmore E, Brammer M, Williams SC, Rabe-Hesketh S, Janot N, David A, et al. Magnetic Resonance in Medicine. 1996;35:261–277
  6. Burgess PW, Shallice T. Response suppression, initiation and strategy use following frontal lobe lesions. Neuropsychologia. 1996;34:263–273
  7. Callicott JH, Ramsey NF, Tallent K, Bertolino A, Knable MB, Coppola R, et al. Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia. Neuropsychopharmacology. 1998;18:186–196
  8. Callicott JH, Bertolino A, Mattay VS, Langheim FJ, Weinberger DR. Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cerebral Cortex. 2000;10:1078–1092
  9. Callicott JH, Mattay VS, Verchinski BA, Marenco S, Egan MF, Weinberger DR. Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down. American Journal of Psychiatry. 2003;160:2209–2215
  10. Carter CS, Mintun M, Nichols T, Cohen JD. Anterior cingulate gyrus dysfunction and selective attention deficits in schizophrenia: [15O] H2O PET study during single-trial Stroop task performance. American Journal of Psychiatry. 1997;154:1670–1675
  11. Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD. Anterior cingulate cortex, error detection, and the online monitoring of performance. Science. 1998;280:747–749
  12. Collette F, Van der Linden M. Brain imaging of the central executive component of working memory. Neuroscience and Biobehavioral Reviews. 2002;26:105–125
  13. Collette F, Van der Linden M, Delfiore G, Degueldre C, Luxen A, Samon E. The functional anatomy of inhibition processes investigated with the Hayling task. NeuroImage. 2001;14:258–267
  14. Corbetta M, Kincade JM, Ollinger JM, McAvoy MP, Shulman GL. Voluntary orienting is dissociated from target detection in human posterior parietal cortex. Nature Neuroscience. 2000;3:292–297
  15. Curtis VA, Bullmore ET, Brammer MJ, Wright IC, Williams SC, Morris RG, et al. Attenuated frontal activation during a verbal fluency task in patients with schizophrenia. American Journal of Psychiatry. 1998;155:1056–1063
  16. Friston KJ, Ashburner J, Frith C, Poline JP, Heather JD, Frackowiak RSJ. Spatial registration and normalization of images. Human Brain Mapping. 1995;3:165–189
  17. Friston KJ, Holmes AP, Worsley KJ, Poline JP, Frith CD, Frackowiak RSJ. Statistical parametric maps in functional imaging: a general linear approach. Human Brain Mapping. 1995;2:189–210
  18. Frith CD. The Cognitive Neuropsychology of Schizophrenia. Hove: Lawrence Erlbaum; 1992;
  19. Garavan H, Ross TJ, Stein EA. Right hemispheric dominance of inhibitory control: an event-related functional MRI study. Proceedings of the National Academy of Sciences of the United States of America. 1999;96:8301–8306
  20. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. NeuroImage. 2002;15:870–878
  21. Glahn DC, Ragland JD, Abramoff A, Barrett J, Laird AR, Bearden CE, et al. Beyond hyponfrontality: a quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia. Human Brain Mapping. 2005;25:60–69
  22. Grady CL, McIntosh AR, Beig S, Keightley ML, Burian H, Black SE. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. The Journal of Neuroscience. 2003;23:986–993
  23. Grapperon J, Delage M. Stroop test and schizophrenia. Encéphale. 1999;25:50–58
  24. Harvey PO, Le Bastard G, Pochon JB, Levy R, Allilaire JF, Dubois B, et al. Executive functions and updating of the contents of working memory in unipolar depression. Journal of Psychiatric Research. 2004;38:567–576
  25. Hasher L, Zacks RT, May CP. Inhibitory control, circadian arousal, and age. In:  Gopher D,  Koriat A editor. Attention and Performance XVIII. Cambridge: MIT Press; 1999;p. 653–675
  26. Hazeltine E, Poldrack R, Gabrieli JDE. Neural activation during response competition. Journal of Cognitive Neuroscience. 2000;12:118–129
  27. Hepp HH, Maier S, Hermle L, Spitzer M. The Stroop effect in schizophrenic patients. Schizophrenia Research. 1996;22:187–195
  28. Hopfinger JB, Buonocore MH, Mangun GR. The neural mechanisms of top-down attentional control. Nature Neuroscience. 2000;3:284–291
  29. Jonides J, Schumacher EH, Smith EE, Koeppe RA, Awh E, Reuter-Lorenz PA, et al. The role of parietal cortex in verbal working memory. Journal of Neuroscience. 1998;18:5026–5034
  30. Manoach DS. Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings. Schizophrenia Research. 2003;6:285–298
  31. Manoach DS, Press DZ, Thangaraj V, Searl MM, Goff DC, Halpern E, et al. Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biological Psychiatry. 1999;43:1128–1137
  32. Manoach DS, Gollub RL, Benson ES, Searl MM, Goff DC, Halpern E, et al. Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biological Psychiatry. 2000;48:99–109
  33. Marczewski P, Van der Linden M. Déficits cognitifs et fonctionnement frontal chez les patients schizophrènes. In:  Van der Linden M,  Seron X,  Le Gall D,  Andres P editor. Neuropsychologie des lobes frontaux. Marseille: Solal; 2001;p. 355–379
  34. May CP, Hasher L, Kane MJ. The role of interference in memory span. Memory & Cognition. 1999;27:759–767
  35. Mazziotta JC, Toga AW, Evans AC, Fox PT, Lancaster JL. Digital brain atlases. Trends of Neuroscience. 1995;18:210–211
  36. McGhie A, Chapman J. Disorders of attention and perception in early schizophrenia. British Journal of Medical Psychology. 1961;34:103–116
  37. McNeely HE, West R, Christensen BK, Alain C. Neurophysiological evidence for disturbances of conflict processing in patients with schizophrenia. Journal of Abnormal Psychology. 2003;112:679–688
  38. Mendrek A, Kiehl KA, Smith AM, Irwin D, Forster BB, Liddle PF. Dysfunction of a distributed neural circuitry in schizophrenia patients during a working-memory performance. Psychological Medicine. 2005;35:187–196
  39. Menon V, Adleman NE, White CD, Glover GH, Reiss AL. Error-related brain activation during a Go/NoGo response inhibition task. Human Brain Mapping. 2001;12:131–143
  40. Morris N, Jones DM. Memory updating in working memory: the role of central executive. British Journal of Psychology. 1990;81:111–121
  41. Nathaniel-James DA, Fletcher P, Frith CD. The functional anatomy of verbal initiation and suppression using the Hayling test. Neuropsychologia. 1997;35:559–566
  42. Oberauer K. Binding and inhibition in working memory: individual and age differences in short-term recognition. Journal of Experimental Psychology. General. 2005;134:368–387
  43. Owen AM. The role of the lateral frontal cortex in mnemonic processing: the contribution of functional neuroimaging. Experimental Brain Research. 2000;133:3304
  44. Owen AM, McMillan KM, Laird AR, Bullmore E. N-Back working memory paradigm: a meta-analysis of normative functional neuroimaging studies. Human Brain Mapping. 2005;25:46–59
  45. Perlstein WM, Carter CS, Noll DC, Cohen JD. fMRI evidence of prefrontal cortex dysfunction in schizophrenia during parametric manipulation working memory load. American Journal of Psychiatry. 2001;158:1105–1113
  46. Peters ER, Pickering AD, Kent A, Glasper A, Irani M, David AS, et al. The relationship between cognitive inhibition and psychotic symptoms. Journal of Abnormal Psychology. 2000;109:386–395
  47. Petrides M, Pandya DN. Projections to the frontal cortex from the parietal region in the rhesus monkey. The Journal of Comparative Neurology. 1984;228:105–116
  48. Rubia K, Russell T, Bullmore ET, Soni W, Brammer MJ, Simmons A, et al. An fMRI study of reduced left prefrontal activation in schizophrenia during normal inhibitory function. Schizophrenia Research. 2001;52:47–55
  49. Sakai K, Rowe JB, Passingham RE. Active maintenance in prefrontal area 46 creates distractor-resistant memory. Nature Neuroscience. 2002;5:479–484
  50. Schooler C, Neumann E, Caplan LJ, Roberts BR. A time course analysis of Stroop interference and facilitation comparing normal individuals and individuals with schizophrenia. Journal of Experimental Psychology. General. 1999;126:37–41
  51. Seidman LJ, Breiter HC, Goodman JM, Goldstein JM, Woodruff PWR, Craven KO, et al. A functional magnetic resonance imaging study of auditory vigilance with low and high information processing demands. Neuropsychology. 1998;12:505–518
  52. Smith EE, Jonides J. Neuroimaging analyses of human working memory. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:12061–12068
  53. Snyder LH, Batista AP, Andersen RA. Coding of intention in the posterior parietal cortex. Nature. 1997;386:167–170
  54. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System — An Approach to Cerebral Imaging. New York: Thieme Medical Publishers; 1988;
  55. Thermenos HW, Seidman LJ, Breiter H, Goldstein JM, Goodman JM, Poldrack R, et al. Functional MRI during auditory verbal working memory in non-psychotic relatives of persons with schizophrenia: a pilot study. Biological Psychiatry. 2004;55:490–500
  56. Weiss EM, Golaszewski S, Mottaghy FM, Hofer A, Hausmann A, Kemmler G, et al. Brain activation patterns during a selective attention test — functional MRI study in healthy volunteers and patients with schizophrenia. Psychiatry Research. Neuroimaging. 2003;123:1–15
  57. Whalley HC, Simonotto E, Flett S, Marshall I, Ebmeier KP, Owens DGC, et al. fMRI correlates of state and trait effects in subjects at genetically enhanced risk of schizophrenia. Brain. 2004;127:478–490
  58. Yücel M, Pantelis C, Stuart GW, Wood SJ, Maruff P, Velakoulis D, et al. Anterior cingulated activation during Stroop task performance: a PET to MRI coregistration study of individual patients with schizophrenia. American Journal of Psychiatry. 2002;159:251–254
  59. Zakzanis KK, Heinrichs RW. Schizophrenia and the frontal brain: a quantitative review. Journal of the International Neuropsychological Society: JINS. 1999;5:556–566

PII: S0925-4927(09)00057-2

doi: 10.1016/j.pscychresns.2009.02.009

Psychiatry Research: Neuroimaging
Volume 173, Issue 3 , Pages 170-176 , 30 September 2009