Psychiatry Research: Neuroimaging
Volume 172, Issue 2 , Pages 99-102 , 15 May 2009

Long-term effects of cognitive behavior therapy on brain activation in spider phobia

  • Anne Schienle

      Affiliations

    • Department of Clinical Psychology, University of Graz, Graz, Austria
    • Bender Institute of Neuroimaging, University of Giessen, Giessen, Germany
    • Corresponding Author InformationCorresponding author. University of Graz, Clinical Psychology, Universitätsplatz 2/III, A-8010 Graz, Austria. Tel.: +43 316 380 5086; fax: +43 316 380 9808.
    • ,
  • Axel Schäfer

      Affiliations

    • Department of Clinical Psychology, University of Graz, Graz, Austria
    • ,
  • Rudolf Stark

      Affiliations

    • Bender Institute of Neuroimaging, University of Giessen, Giessen, Germany
    • ,
  • Dieter Vaitl

      Affiliations

    • Bender Institute of Neuroimaging, University of Giessen, Giessen, Germany

Received 10 September 2007 ,Revised 27 October 2008 ,Accepted 12 November 2008.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th edition. Washington DC: APA; 1994;
  2. Arntz A, Lavy E. Does stimulus elaboration potentiate exposure in vivo treatment? Two forms of one-session treatment of spider phobia. Behavioural Psychotherapy. 1993;21:1–12
  3. Deichmann R, Gottfried JA, Hutton C, Turner R. Optimized EPI for fMRI studies of the orbitofrontal cortex. Neuroimage. 2003;19:430–441
  4. Choy Y, Fyer AJ, Lipsitz J. Treatment of specific phobia in adults. Clinical Psychology Review. 2007;27:266–286
  5. Gotestam KG, Hokstad A. One session treatment of spider phobia in a group setting with rotating active exposure. European Journal of Psychiatry. 2002;16:129–134
  6. Hellström K, Öst LG. One session therapist directed exposure vs. two forms of manual directed self-exposure in the treatment of spider phobia. Behaviour Research and Therapy. 1995;33:959–965
  7. Klorman R, Weerts T, Hastings J, Melamed B, Lang P. Psychometric description of some fear-specific questionnaires. Behavior Research. 1974;5:401–409
  8. Koch E, Spates R, Himle J. Comparison of behavioral and cognitive-behavioral one-session exposure treatments for small animal phobias. Behaviour Research and Therapy. 2004;42:1483–1504
  9. Kringelbach ML, Rolls ET. The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology. Progress in Neurobiology. 2004;72:341–372
  10. Lang PJ, Bradley M, Cuthbert B. International Affective Picture System. Center for Research in Psychophysiology. Gainesville: University of Florida; 1997;
  11. Larson CL, Schaefer HS, Siegle GJ, Jackson CAB, Anderle MJ, Davidson RJ. Fear is fast in phobic individuals: amygdala activation in response to fear-relevant stimuli. Biological Psychiatry. 2006;60:410–417
  12. LeDoux J. Synaptic Self. How Our Brains Become What We Are. London: Penguin Books; 2002;
  13. Margraf J. Diagnostisches Kurz-Interview bei psychischen Störungen. MiniDIPS. Berlin: Springer-Verlag; 1994;
  14. O'Doherty JP, Kringelbach ML, Rolls ET, Hornak J, Andrews C. Abstract reward and punishment representations in the human orbitofrontal cortex. Nature Neuroscience. 2001;4:95–102
  15. Öst LG. One-session group treatment of spider phobia. Behaviour Research and Therapy. 1996;34:707–715
  16. Öst LG, Salkovskis PM, Hellstrom K. One-session therapist directed exposure vs. self-exposure in the treatment of spider phobia. Behavior Therapy. 1991;22:407–422
  17. Öst LG, Ferebee I, Furmark T. One-session group therapy of spider phobia: direct versus indirect treatments. Behaviour Research and Therapy. 1997;35:721–732
  18. Paquette V, Lévesque J, Mensour B, Leroux JM, Beaudoin G, Bourgouin P, et al. Change the mind and you change the brain: effects of cognitive behavioral therapy on the neural correlates of spider phobia. Neuroimage. 2003;18:401–409
  19. Rolls ET. The orbitofrontal cortex and reward. Cerebral Cortex. 2000;10:284–294
  20. Schienle A, Walter B, Schäfer A, Stark R, Vaitl D. Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures. Neuroscience Letters. 2005;388:1–6
  21. Schienle A, Schäfer A, Hermann A, Rohrmann S, Vaitl D. Symptom provocation and symptom reduction in spider phobia. European Archives of Psychiatry and Clinical Neuroscience. 2007;257:486–493
  22. Small D, Zatorre R, Dagher A, Evans AC, Jones-Gotman M. Changes in brain activity related to eating chocolate: from pleasure to aversion. Brain. 2000;124:1720–1733
  23. Stark R, Schienle A, Walter B, Kirsch P, Blecker C, Ott U, et al. The hemodynamic effects of negative emotional pictures — a test–retest analysis. Neuropsychobiology,. 2004;50:108–118
  24. Straube T, Glauer M, Dilger S, Mentzel HJ, Miltner WHR. Effects of cognitive-behavioral therapy on brain activation in specific phobia. Neuroimage. 2006;29:125–135
  25. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15:273–289
  26. Walter B, Blecker C, Kirsch P, Sammer G, Schienle A, Stark R. MARINA: an easy to use tool for the creation of MAsks for Region of INterest Analyses. Neuroimage. 2003;19:(CD-ROM)

☆ The study was carried out at: Bender Institute of Neuroimaging.

PII: S0925-4927(08)00187-X

doi: 10.1016/j.pscychresns.2008.11.005

Psychiatry Research: Neuroimaging
Volume 172, Issue 2 , Pages 99-102 , 15 May 2009

Article Tools

* Image Usage & Resolution