Psychiatry Research: Neuroimaging
Volume 164, Issue 1 , Pages 86-89 , 30 October 2008

Medial temporal N-acetyl-aspartate in pediatric major depression

  • Frank P. MacMaster

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • ,
  • Gregory J. Moore

      Affiliations

    • Departments of Psychiatry and Radiology, Penn State College of Medicine, Hershey, PA, 17033, USA
    • ,
  • Aileen Russell

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • ,
  • Yousha Mirza

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • ,
  • S. Preeya Taormina

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • ,
  • Christian Buhagiar

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • ,
  • David R. Rosenberg

      Affiliations

    • Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA
    • Department of Psychiatry, Children's Hospital of Michigan, Detroit, MI, 48201, USA
    • Corresponding Author InformationCorresponding author. Psychiatry 9B-UHC; 4201 St. Antoine Boulevard, Detroit, MI 48201, USA. Tel.: +1 313 577 9000; fax: +1 313 577 5900.

Received 27 August 2007 ,Revised 21 December 2007 ,Accepted 22 December 2007.

References 

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  2. Dahl RE, Ryan ND, Puig-Antich J, Nguyen NA, al-Shabbout M, Meyer VA, et al. 24-hour cortisol measures in adolescents with major depression: a controlled study. Biological Psychiatry. 1991;30:25–36
  3. Duyn JH, Moonen CT. Fast proton spectroscopic imaging of human brain using multiple spin-echoes. Magnetic Resonance in Medicine. 1993;30:409–414
  4. Farchione TR, Moore GJ, Rosenberg DR. Proton magnetic resonance spectroscopic imaging in pediatric major depression. Biological Psychiatry. 2002;52:86–92
  5. Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, et al. Schedule for Affective Disorders and Schizophrenia for School-age Children—Present and Lifetime Versions (K-SADS-PL): initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry. 1997;36:980–988
  6. Kutcher S, Malkin D, Silverberg J, Marton P, Williamson P, Malkin A, et al. Nocturnal cortisol, thyroid stimulating hormone, and growth hormone secretory profiles in depressed adolescents. Journal of the American Academy of Child and Adolescent Psychiatry. 1991;30:407–414
  7. MacMaster FP, Kusumakar V. Hippocampal volume in early onset depression. BMC Medicine. 2004;2:2
  8. MacMaster FP, Mirza Y, Szeszko PR, Kmiecik LE, Easter PC, Taormina SP, et al. Amygdala and hippocampal volumes in familial pediatric major depressive disorder. Biological Psychiatry. 2008;63(4):385–390
  9. MacQueen GM, Campbell S, McEwen BS, Macdonald K, Amano S, Joffe RT, et al. Course of illness, hippocampal function, and hippocampal volume in major depression. Proceedings of the National Academy of Sciences of the United States of America. 2003;100:1387–1392
  10. Rosso IM, Cintron CM, Steingard RJ, Renshaw PF, Young AD, Yurgelun-Todd DA. Amygdala and hippocampus volumes in pediatric major depression. Biological Psychiatry. 2005;57:21–26
  11. Soares JC, Mann JJ. The anatomy of mood disorders—review of structural neuroimaging studies. Biological Psychiatry. 1997;41:86–106
  12. Sapolsky RM. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biological Psychiatry. 2000;48:755–765
  13. Sheline YI, Sanghavi M, Mintun MA, Gado MH. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. Journal of Neuroscience. 1999;19:5034–5043
  14. Smith EA, Russell A, Lorch E, Banerjee SP, Rose M, Ivey J, et al. Increased medial thalamic choline found in pediatric patients with obsessive–compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study. Biological Psychiatry. 2003;54:1399–1405
  15. Soher BJ, Hurd RE, Sailasuta N, Barker PB. Quantitation of automated single-voxel proton MRS using cerebral water as an internal reference. Magnetic Resonance in Medicine. 1996;36:335–339

PII: S0925-4927(08)00002-4

doi: 10.1016/j.pscychresns.2007.12.022

Psychiatry Research: Neuroimaging
Volume 164, Issue 1 , Pages 86-89 , 30 October 2008

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