Psychiatry Research: Neuroimaging
Volume 163, Issue 2 , Pages 143-155 , 15 July 2008

Prefrontal mechanisms for executive control over emotional distraction are altered in major depression

  • Lihong Wang

      Affiliations

    • Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, USA
    • Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC, USA
  • ,
  • Kevin S. LaBar

      Affiliations

    • Center for Cognitive Neuroscience, Duke University, Durham, NC, USA
  • ,
  • Moria Smoski

      Affiliations

    • Cognitive Behavioral Research and Treatment Program, Duke University Medical Center, Durham, NC, USA
  • ,
  • M. Zachary Rosenthal

      Affiliations

    • Cognitive Behavioral Research and Treatment Program, Duke University Medical Center, Durham, NC, USA
  • ,
  • Florin Dolcos

      Affiliations

    • Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, USA
  • ,
  • Thomas R. Lynch

      Affiliations

    • Cognitive Behavioral Research and Treatment Program, Duke University Medical Center, Durham, NC, USA
  • ,
  • Ranga R. Krishnan

      Affiliations

    • Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC, USA
  • ,
  • Gregory McCarthy

      Affiliations

    • Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, USA
    • Department of Veterans Affairs Medical Center, Durham, NC, USA
    • Department of Psychology, Yale University, New Haven, CT, USA
    • Corresponding Author InformationCorresponding author. Department of Psychology, Yale University, 2 Hillhouse Ave., New Haven, CT 06511, USA. Tel.: +1 203 432 7435; fax: +1 203 432 7172.

Received 4 June 2007 ,Revised 22 September 2007 ,Accepted 25 October 2007.

References 

  1. Aron AR, Robbins TW, Poldrack RA. Inhibition and the right inferior frontal cortex. Trends in Cognitive Sciences. 2004;8:170–177
  2. Barch DM, Braver TS, Sabb FW, Noll DC. Anterior cingulate and the monitoriing of response conflict: evidence from an fMRI study of overt verb generation. Journal of Cognitive Neuroscience. 2000;12:298–309
  3. Bishop S, Duncan J, Brett M, Lawrence AD. Prefrontal cortical function and anxiety: controlling attention to threat-related stimuli. Nature Neuroscience. 2004;7:184–188
  4. Botvinick M, Nystrom LE, Fissell K, Carter CS, Cohen JD. Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature. 1999;402:179–181
  5. Botvinick MM, Braver TS, Barch DM, Carter CS, Cohen JD. Conflict monitoring and cognitive control. Psychological Review. 2001;108:624–652
  6. Canli T, Cooney RE, Goldin P, Shah M, Sivers H, Thomason ME, et al. Amygdala reactivity to emotional faces predicts improvement in major depression. Neuroreport. 2005;16:1267–1270
  7. Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD. Anterior cingulate cortex, error detection, and the online monitoring of performance. Science. 1998;280:747–749
  8. Carter CS, Macdonald AM, Botvinick M, Ross LL, Stenger VA, Noll D, et al. Parsing executive processes: strategic vs. evaluative functions of the anterior cingulate cortex. Proceedings of the National Academy of Sciences of the United States of America. 2000;97:1944–1948
  9. Cohen JD, Botvinick M, Carter CS. Anterior cingulate and prefrontal cortex: who's in control?. Nature Neuroscience. 2000;3:421–423
  10. D'Esposito M, Postle BR, Jonides J, Smith EE. The neural substrate and temporal dynamics of interference effects in working memory as revealed by event-related functional MRI. Proceedings of the National Academy of Sciences of the United States of America. 1999;96:7514–7519
  11. Davidson RJ, Irwin W, Anderle MJ, Kalin NH. The neural substrates of affective processing in depressed patients treated with venlafaxine. American Journal of Psychiatry. 2003;160:64–75
  12. Dolan RJ, Bench CJ, Liddle PF, Friston KJ, Frith CD, Grasby PM, et al. Dorsolateral prefrontal cortex dysfunction in the major psychoses: symptom or disease specificity?. Journal of Neurology, Neurosurgery & Psychiatry. 1993;56:1290–1294
  13. Dolcos F, McCarthy G. Brain systems mediating cognitive interference by emotional distraction. Journal of Neuroscience. 2006;26:2072–2079
  14. Drevets WC. Prefrontal cortical-amygdalar metabolism in major depression. Annals of the New York Academy of Sciences. 1999;877:614–637
  15. Drevets WC, Raichle ME. Reciprocal suppression of regional cerebral blood flow during emotional versus higher cognitive processes: implications for interactions between emotion and cognition. Cognition and Emotion. 1998;12:353–385
  16. Ellenbogen MA, Schwartzman AE, Stewart J, Walker CD. Stress and selective attention: the interplay of mood, cortisol levels, and emotional information processing. Psychophysiology. 2002;39:723–732
  17. Elliott R, Sahakian BJ, Herrod JJ, Robbins TW, Paykel ES. Abnormal response to negative feedback in unipolar depression: evidence for a diagnosis specific impairment. Journal of Neurology, Neurosurgery & Psychiatry. 1997;63:74–82
  18. Elliott R, Rubinsztein JS, Sahakian BJ, Dolan RJ. Selective attention to emotional stimuli in a verbal go/no-go task: an fMRI study. NeuroReport. 2000;11:1739–1744
  19. Elliott R, Rubinsztein JS, Sahakian BJ, Dolan RJ. The neural basis of mood-congruent processing biases in depression. Archives of General Psychiatry. 2002;59:597–604
  20. Etkin A, Egner T, Peraza DM, Kandel ER, Hirsch J. Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala. Neuron. 2006;51:871–882
  21. First M, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders. New York: Biometrics Research, New York State Psychiatric Institute; 1995;
  22. Fu CH, Williams SC, Cleare AJ, Brammer MJ, Walsh ND, Kim J, et al. Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study. Archives of General Psychiatry. 2004;61:877–889
  23. Fu CH, Williams SC, Brammer MJ, Suckling J, Kim J, Cleare AJ, et al. Neural responses to happy facial expressions in major depression following antidepressant treatment. American Journal of Psychiatry. 2007;164:599–607
  24. Garavan H, Ross TJ, Murphy K, Roche RA, Stein EA. Dissociable executive functions in the dynamic control of behavior: inhibition, error detection, and correction. NeuroImage. 2002;17:1820–1829
  25. George MS, Ketter TA, Parekh PI, Rosinsky N, Ring HA, Pazzaglia PJ, et al. Blunted left cingulate activation in mood disorder subjects during a response interference task (the Stroop). Journal of Neuropsychiatry & Clinical Neurosciences. 1997;9:55–63
  26. Hamilton M. A rating scale for depression. Journal of Neurology, Neurosurgery & Psychiatry. 1960;23:56–62
  27. Harvey PO, Fossati P, Pochon JB, Levy R, Lebastard G, Lehericy S, et al. Cognitive control and brain resources in major depression: an fMRI study using the n-back task. NeuroImage. 2005;26:860–869
  28. Johnson MK, Raye CL, Mitchell KJ, Greene EJ, Cunningham WA, Sanislow CA. Using fMRI to investigate a component process of reflection: prefrontal correlates of refreshing a just-activated representation. Cognitive, Affective & Behavioral Neuroscience. 2005;5:339–361
  29. Jonides J, Smith EE, Marshuetz C, Koeppe RA, Reuter-Lorenz PA. Inhibition in verbal working memory revealed by brain activation. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:8410–8413
  30. Keedwell PA, Andrew C, Williams SC, Brammer MJ, Phillips ML. A double dissociation of ventromedial prefrontal cortical responses to sad and happy stimuli in depressed and healthy individuals. Biological Psychiatry. 2005;58:495–503
  31. Konishi S, Nakajima K, Urchida I, Kameyama M, Nakahara K, Sekihara K, et al. Transient activation of inferior prefrontal cortex during cognitive set shifting. Nature Neuroscience. 1998;1:80–94
  32. Liddle PF, Kiehl KA, Smith AM. Event-related fMRI study of response inhibition. Human Brain Mapping. 2001;12:100–109
  33. Lyubomirsky S, Caldwell ND, Nolen-Hoeksema S. Effects of ruminative and distracting responses to depressed mood on retrieval of autobiographical memories. Journal of Personality & Social Psychology. 1998;75:166–177
  34. Mather M, Mitchell KJ, Raye CL, Novak DL, Greene EJ, Johnson MK. Emotional arousal can impair feature binding in working memory. Journal of Cognitive Neuroscience. 2006;18:614–625
  35. Matsuo K, Glahn DC, Peluso MA, Hatch JP, Monkul ES, Najt P, et al. Prefrontal hyperactivation during working memory task in untreated individuals with major depressive disorder. Molecular Psychiatry. 2006;12:158–166
  36. Mayberg HS. Limbic–cortical dysregulation: a proposed model of depression. Journal of Neuropsychiatry & Clinical Neurosciences. 1997;9:471–481
  37. Mayberg HS, Lewis PJ, Regenold W, Wagner HN. Paralimbic hypoperfusion in unipolar depression. Journal of Nuclear Medicine. 1994;35:929–934
  38. Mayberg HS, Brannan SK, Tekell JL, Silva JA, Mahurin RK, McGinnis S, et al. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biological Psychiatry. 2000;48:830–843
  39. McKiernan KA, Kaufman JN, Kucera-Thompson J, Binder JR. A parametric manipulation of factors affecting task-induced deactivation in functional neuroimaging. Journal of Cognitive Neuroscience. 2003;15:394–408
  40. Miller IW, Bishop S, Norman WH, Maddever H. The modified Hamilton Rating Scale for Depression: reliability and validity. Psychiatry Research. 1985;14:131–142
  41. Ottowitz WE, Dougherty DD, Savage CR. The neural network basis for abnormalities of attention and executive function in major depressive disorder: implications for application of the medical disease model to psychiatric disorders. Harvard Review of Psychiatry. 2002;10:86–99
  42. Pelphrey KA, Mitchell TV, McKeown MJ, Goldstein J, Allison T, McCarthy G. Brain activity evoked by the perception of human walking: controlling for meaningful coherent motion. Journal of Neuroscience. 2003;23:6819–6825
  43. Posner MI, Dehaene S. Attentional networks. Trends in Neurosciences. 1994;17:75–79
  44. Robins LN, Helzer JE, Croughan J, Ratcliff KS. National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. Archives of General Psychiatry. 1981;38:381–389
  45. Rogers MA, Kasai K, Koji M, Fukuda R, Iwanami A, Nakagome K, et al. Executive and prefrontal dysfunction in unipolar depression: a review of neuropsychological and imaging evidence. Neuroscience Research. 2004;50:1–11
  46. Rubia K, Smith AB, Brammer MJ, Taylor E. Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection. NeuroImage. 2003;20:351–358
  47. Schmitz N, Rubia K, Daly E, Smith A, Williams S, Murphy DG. Neural correlates of executive function in autistic spectrum disorders. Biological Psychiatry. 2006;59:7–16
  48. Shafritz KM, Collins SH, Blumberg HP. The interaction of emotional and cognitive neural systems in emotionally guided response inhibition. NeuroImage. 2006;31:468–475
  49. Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA. Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biological Psychiatry. 2001;50:651–658
  50. Siegle GJ, Steinhauer SR, Thase ME, Stenger VA, Carter CS. Can't shake that feeling: event-related fMRI assessment of sustained amygdala activity in response to emotional information in depressed individuals. Biological Psychiatry. 2002;51:693–707
  51. Siegle GJ, Carter CS, Thase ME. Use of FMRI to predict recovery from unipolar depression with cognitive behavior therapy. American Journal of Psychiatry. 2006;163:735–738
  52. Smith EE, Jonides J. Storage and executive processes in the frontal lobes. Science. 1999;283:1657–1661
  53. Surguladze S, Brammer MJ, Keedwell P, Giampietro V, Young AW, Travis MJ, et al. A differential pattern of neural response toward sad versus happy facial expressions in major depressive disorder. Biological Psychiatry. 2005;57:201–209
  54. Wagner G, Sinsel E, Sobanski T, Kohler S, Marinou V, Mentzel HJ, et al. Cortical inefficiency in patients with unipolar depression: an event-related FMRI study with the Stroop task. Biological Psychiatry. 2006;59:958–965
  55. Wang L, McCarthy G, Song AW, LaBar KS. Amygdala activation to sad pictures during high-field (4 tesla) functional magnetic resonance imaging. Emotion. 2005;5:12–22
  56. Wang L, LaBar KS, McCarthy G. Mood alters amygdala activation to sad distractors during an attentional task. Biological Psychiatry. 2006;15:1139–1146
  57. Wenzlaff RM, Bates DE. Unmasking a cognitive vulnerability to depression: how lapses in mental control reveal depressive thinking. Journal of Personality & Social Psychology. 1998;75:1559–1571
  58. Whalen PJ, Bush G, McNally RJ, Wilhelm S, McInerney SC, Jenike MA, et al. The emotional counting Stroop paradigm: a functional magnetic resonance imaging probe of the anterior cingulate affective division. Biological Psychiatry. 1998;44:1219–1228

PII: S0925-4927(07)00224-7

doi: 10.1016/j.pscychresns.2007.10.004

Psychiatry Research: Neuroimaging
Volume 163, Issue 2 , Pages 143-155 , 15 July 2008