Psychiatry Research: Neuroimaging
Volume 162, Issue 3 , Pages 256-261 , 15 April 2008

Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study

  • Andrea P. Jackowski

      Affiliations

    • Child Study Center, Yale University School of Medicine, New Haven, CT, United States
    • LiNC, Universidade Federal de São Paulo, São Paulo, Brazil
  • ,
  • Heather Douglas-Palumberi

      Affiliations

    • Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States
  • ,
  • Marcel Jackowski

      Affiliations

    • Institute of Mathematics and Statistics, University of São Paulo, CEP 05508-090, São Paulo, Brazil
  • ,
  • Lawrence Win

      Affiliations

    • Child Study Center, Yale University School of Medicine, New Haven, CT, United States
  • ,
  • Robert T. Schultz

      Affiliations

    • Child Study Center, Yale University School of Medicine, New Haven, CT, United States
  • ,
  • Lawrence W. Staib

      Affiliations

    • Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, United States
  • ,
  • John H. Krystal

      Affiliations

    • Child Study Center, Yale University School of Medicine, New Haven, CT, United States
  • ,
  • Joan Kaufman

      Affiliations

    • Child Study Center, Yale University School of Medicine, New Haven, CT, United States
    • Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 203 764 9949;fax: +1 203 7649990.

Received 8 August 2007 ,Accepted 9 August 2007.

References 

  1. Birmaher B, Khetarpol S, Brent D, Cully M, Balach L, Kaufman J, et al. The Screen for Child Anxiety Related Emotional Disorders (SCARED): scale construction and psychometric properties. Journal of the American Academy of Child and Adolescent Psychiatry. 1997;36:545–553
  2. Bremner JD. The relationship between cognitive and brain changes in posttraumatic stress disorder. Annals of the New York Academy of Sciences. 2006;1071:80–86
  3. Canli T, Qiu M, Omura K, Congdon E, Haas BW, Amin Z, et al. Neural correlates of epigenesis. Proceedings of the National Academy of Sciences of the United States of America. 2006;103(43):16033–16038(Epub 12006 Oct 16010)
  4. Carrion VG, Weems CF, Eliez S, Patwardhan A, Brown W, Ray RD, et al. Attenuation of frontal asymmetry in pediatric posttraumatic stress disorder. Biological Psychiatry. 2001;50:943–951
  5. De Bellis MD, Keshavan MS, Shifflett H, Iyengar S, Beers SR, Hall J, et al. Brain structures in pediatric maltreatment-related posttraumatic stress disorder: a sociodemographically matched study. Biological Psychiatry. 2002;52:1066–1078
  6. De Bellis MD, Keshavan MS, Clark DB, Casey BJ, Giedd JN, Boring AM, et al. Developmental traumatology. Part II: brain development. Biological Psychiatry. 1999;45:1271–1284
  7. de Geus EJ, van't Ent D, Wolfensberger SP, Heutink P, Hoogendijk WJ, Boomsma DI, et al. Intrapair differences in hippocampal volume in monozygotic twins discordant for the risk for anxiety and depression. Biological Psychiatry. 2007;61(9):1062–1071
  8. Giedd JN, Snell JW, Lange N, Rajapakse JC, Casey BJ, Kozuch PL, et al. Quantitative magnetic resonance imaging of human brain development: ages 4–18. Cerebral Cortex. 1996;6:551–560
  9. Hariri AR, Weinberger DR. Imaging genomics. British Medical Bulletin. 2003;65:259–270
  10. Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry. 1997;36:980–988
  11. Kaufman J, Plotsky P, Nemeroff C, Charney D. Effects of early adverse experience on brain structure and function: clinical implications. Biological Psychiatry. 2000;48:778–790
  12. Kaufman J, Blumberg HP, Young CM. Neurobiology of early onset mood disorders. In:  Charney DS,  Nestler EJ editor. Neurobiology of Mental Illness. 2nd ed.. New York: Oxford University Press; 2004;
  13. Kaufman J, Yang BZ, Douglas-Palumberi H, Grasso D, Lipschitz D, Houshyar S, et al. Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biological Psychiatry. 2006;59:673–680
  14. Lauder JM. Hormonal and humoral influences on brain development. Psychoneuroendocrinology. 1983;8:121–155
  15. Molnar BE, Buka SL, Kessler RC. Child sexual abuse and subsequent psychopathology: results from the National Comorbidity Survey. American Journal of Public Health. 2001;91:753–760
  16. Oouchi H, Yamada K, Sakai K, Kizu O, Kubota T, Ito H, et al. Diffusion anisotropy measurement of brain white matter is affected by voxel size: underestimation occurs in areas with crossing fibers. American Journal of Neuroradiology. 2007;28:1102–1106
  17. Pandya DN, Seltzer B. The topography of commisural fibers. In:  Lepore F,  Ptito M,  Jasper HH editor. Two Hemispheres — One Brain: Functions of the Corpus Callosum. vol 17:Inc., New York: Alan R. Liss; 1986;p. 47–74
  18. Papadakis NG, Xing D, Huang CLH, Hall LD, Carpenter TA. A comparative study of acquisition schemes for diffusion tensor imaging using MRI. Journal of Magnetic Resonance. 1999;137:67–82
  19. Papademetris, X., Jackowski, M., Rajeevan, N., Constable, R.T., Staib, L., 2006. Bioimage Suite, Yale Department of Diagnostic Imaging. In http://www.bioimagesuite.org(ed).
  20. Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy. Magnetic Resonance in Medicine. 1996;36(6):893–906
  21. Pine DS, Mogg K, Bradley BP, Montgomery L, Monk CS, McClure E, et al. Attention bias to threat in maltreated children: implications for vulnerability to stress-related psychopathology. American Journal of Psychiatry. 2005;162:291–296
  22. Raine A, Lencz T, Taylor K, Hellige JB, Bihrle S, Lacasse L, et al. Corpus callosum abnormalities in psychopathic antisocial individuals. Archives of Journal Psychiatry. 2003;60(11):1134–1142
  23. Sanchez MM, Hearn EF, Do D, Rilling JK, Herndon JG. Differential rearing affects corpus callosum size and cognitive function of rhesus monkeys. Brain Research. 1998;812:38–49
  24. Smith SM, Johansen-Berg H, Jenkinson M, Rueckert D, Nichols TE, Miller KL, et al. Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics. Nature Protocols. 2007;2:499–504
  25. Teicher MH, Andersen SL, Polcari A, Andersen SL, Dumont N, Ackerman E. Developmental neurobiology of childhood stress and trauma. Psychiatric Clinics of North America. 2002;25:397–426
  26. Teicher MH, Dumont NL, Ito Y, Vaituzis C, Giedd JN, Andersen SL. Childhood neglect is associated with reduced corpus callosum area. Biological Psychiatry. 2004;56:80–85
  27. Teicher MH, Ito Y, Glod CA, et al. Preliminary evidence for abnormal cortical development in physically and sexually abused children using EEG coherence and MRI. Annals of the New York Academy of Sciences. 1997;821:160–175
  28. Tupler LA, De Bellis MD. Segmented hippocampal volume in children and adolescents with posttraumatic stress disorder. Biological Psychiatry. 2006;59:523–529
  29. Villarreal G, Hamilton DA, Graham DP, Driscoll I, Qualls C, Petropoulos H, et al. Reduced area of the corpus callosum in posttraumatic stress disorder. Psychiatry Research. 2004;131:227–235
  30. Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain. 1989;112:799–835

PII: S0925-4927(07)00156-4

doi: 10.1016/j.pscychresns.2007.08.006

Psychiatry Research: Neuroimaging
Volume 162, Issue 3 , Pages 256-261 , 15 April 2008