Psychiatry Research: Neuroimaging
Volume 156, Issue 3 , Page 275, 15 December 2007

Erratum to “Psychomotor slowing in older patients with major depression: Relationships with blood flow in the caudate nucleus and white matter lesions” [Psychiatry Research: Neuroimaging 155(3)(2007)211–220]

  • Ian B. Hickie

      Affiliations

    • Brain and Mind Research Institute, 100 Mallett Street, Camperdown, NSW 2050, Australia
    • Corresponding Author InformationCorresponding author. Brain and Mind Research Institute, 100 Mallett Street, Camperdown, NSW 2050, Australia. Tel.: +61 2 9351 0799; fax: +61 2 9351 0652.
    • ,
  • Sharon L. Naismith

      Affiliations

    • Brain and Mind Research Institute, 100 Mallett Street, Camperdown, NSW 2050, Australia
    • ,
  • Philip B. Ward

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • ,
  • Craig L. Little

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • ,
  • Mark Pearson

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • ,
  • Elizabeth M. Scott

      Affiliations

    • Brain and Mind Research Institute, 100 Mallett Street, Camperdown, NSW 2050, Australia
    • ,
  • Philip Mitchell

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • Black Dog Institute, Sydney, Australia
    • ,
  • Kay Wilhelm

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • ,
  • Gordon Parker

      Affiliations

    • School of Psychiatry, University of New South Wales, Sydney, Australia
    • Black Dog Institute, Sydney, Australia

Article Outline

 

The editors regret that there were two minor errors in the abstract of this article. The abstract should read as follows:

Selected structural and functional neuroimaging correlates of psychomotor slowing were examined in older persons with depression. Clinical, neuropsychological, magnetic resonance imaging (MRI) and single photon emission computerized tomography (SPECT) data were obtained for 32 persons with depression (mean age=55.5) and 17 controls (mean age=55.4). Psychomotor slowing was measured by simple (SRT) and choice (CRT) reaction times. White matter lesions (WMLs) were visually rated and caudate nucleus regional cerebral blood flow (rCBF) was obtained through the co-registration of MRI and SPECT data. Two SPECT scans were performed (corresponding to the SRT and CRT tasks) and a percentage change score in rCBF (%rCBF) due to the increasing complexity of the second task was calculated. Persons with depression and controls did not differ with respect to %rCBF or frequency of WMLs. In persons with depression, reduced %rCBF was associated with slower CRT. For all subjects, WMLs predicted 14% of the variance in %rCBF. Although CRT was predicted by a combination of older age, WMLs and rCBF%, the diagnosis of depression still predicted a further 25% of the variance. Reduced %rCBF is associated with demonstrable psychomotor slowing and presence of WMLs. While psychomotor slowing is determined in part by subcortical changes, other cortical and illness-dependent factors are likely to be relevant.

PII: S0925-4927(07)00154-0

doi:10.1016/j.pscychresns.2007.08.001

Refers to article:

  • Psychomotor slowing in older patients with major depression: Relationships with blood flow in the caudate nucleus and white matter lesions

    Ian B. Hickie, Sharon L. Naismith, Philip B. Ward, Craig L. Little, Mark Pearson, Elizabeth M. Scott, Philip Mitchell, Kay Wilhelm, Gordon Parker
    Psychiatry Research: Neuroimaging 15 August 2007 (Vol. 155, Issue 3, Pages 211-220)

Psychiatry Research: Neuroimaging
Volume 156, Issue 3 , Page 275, 15 December 2007

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