Psychiatry Research: Neuroimaging
Volume 163, Issue 3 , Pages 270-278 , 30 August 2008

Differential abnormalities of the head and body of the caudate nucleus in attention deficit-hyperactivity disorder

  • Virginia Tremols

      Affiliations

    • Unitat de Recerca en Neurociencia Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autonoma Barcelona, Centre Fòrum. Hospital del Mar, Carrer Llull 410, 08019 Barcelona, Spain
    • Departament de Pediatria USP Institut Universitari Dexeus, Angli 31, 08017 Barcelona, Spain
    • ,
  • Anna Bielsa

      Affiliations

    • Unitat de Paidopsiquiatria. Hospital Vall d'Hebron, Passeig de Vall d'Hebron 171, 08035 Barcelona, Spain
    • ,
  • Joan-Carles Soliva

      Affiliations

    • Unitat de Recerca en Neurociencia Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autonoma Barcelona, Centre Fòrum. Hospital del Mar, Carrer Llull 410, 08019 Barcelona, Spain
    • ,
  • Carol Raheb

      Affiliations

    • Unitat de Paidopsiquiatria. Hospital Vall d'Hebron, Passeig de Vall d'Hebron 171, 08035 Barcelona, Spain
    • ,
  • Susanna Carmona

      Affiliations

    • Unitat de Recerca en Neurociencia Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autonoma Barcelona, Centre Fòrum. Hospital del Mar, Carrer Llull 410, 08019 Barcelona, Spain
    • ,
  • Josep Tomas

      Affiliations

    • Unitat de Paidopsiquiatria. Hospital Vall d'Hebron, Passeig de Vall d'Hebron 171, 08035 Barcelona, Spain
    • ,
  • Joan-Domingo Gispert

      Affiliations

    • Institut d'Alta Tecnologia-Parc de Recerca Biomèdica de Barcelona, Passeig Marítim 25-29, 08003 Barcelona, Spain
    • ,
  • Mariana Rovira

      Affiliations

    • CRC Corporacio Sanitaria, Barcelona, Spain
    • ,
  • Jordi Fauquet

      Affiliations

    • Departament de Psicobiologia i de Metodologia de les Ciències de la Salut Universitat Autonoma Barcelona, 08193 Bellaterra, Spain
    • ,
  • Adolf Tobeña

      Affiliations

    • Unitat de Recerca en Neurociencia Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autonoma Barcelona, Centre Fòrum. Hospital del Mar, Carrer Llull 410, 08019 Barcelona, Spain
    • ,
  • Antoni Bulbena

      Affiliations

    • Institut d'Atenció Psiquiàtrica, IMAS, Passeig Marítim 25-29 08003 Barcelona, Spain
    • ,
  • Oscar Vilarroya

      Affiliations

    • Unitat de Recerca en Neurociencia Cognitiva, Departament de Psiquiatria i Medicina Legal, Universitat Autonoma Barcelona, Centre Fòrum. Hospital del Mar, Carrer Llull 410, 08019 Barcelona, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 932 541 313; fax: +34 932 541 315.

Received 3 March 2006 ,Revised 14 March 2007 ,Accepted 22 April 2007.

References 

  1. Achenbach TM, Ruffle TM. The Child Behavior Checklist and related forms for assessing behavioral/emotional problems and competencies. Pediatr. Rev. 2000;21:265–271
  2. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 1986;9:357–381
  3. Alexander GE, Crutcher MD, DeLong MR. Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, “prefrontal” and “limbic” functions. Prog. Brain Res. 1990;85:119–146
  4. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. Washington, DC: Author; 2000;
  5. Aylward EH, Reiss AL, Reader MJ, Singer H, Brown JE, Denckla MB. Basal ganglia volumes in children with attention-deficit hyperactivity disorder. J. Child Neurol. 1996;11:112–115
  6. Barkley RA. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol. Bull. 1997;121:65–94
  7. Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, et al. Caudate infarcts. Arch. Neurol. 1990;47:133–143
  8. Carmona S, Vilarroya O, Bielsa A, Trèmols V, Soliva JC, Rovira M, et al. Global and regional gray matter reductions in ADHD: a voxel-based morphometric study. Neurosci. Lett. 2005;389:88–93
  9. Castellanos FX, Giedd JN, Eckburg P, Marsh WL, Vaituzis AC, Kaysen D, et al. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. Am. J. Psychiatry. 1994;151:1791–1796
  10. Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Vaituzis AC, Dickstein DP, et al. Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder. Arch. Gen. Psychiatry. 1996;53(7):607–616
  11. Conners C, Sitarenios G, Parker JD, Epstein JN. The revised Conners parent rating scale (CPRS-R): factor structure, reliability, and criterion validity. J. Abnorm. Child Psychol. 1998;26(4):257–268
  12. Conners C, Sitarenios G, Parker JD, Epstein JN. Revision and restandardization of the Conners teacher rating scale (CtRS-R): factor structure, reliability, and criterion validity. J. Abnorm. Child Psychol. 1998;26(4):279–291
  13. Dreifuss S, Lazeyras FJ, Andino F, Spinelli SG, Delavelle L, Seeck J. Volumetric measurements of subcortical nuclei in patients with temporal lobe epilepsy. Neurology. 2001;57(9):1636–1641
  14. Durston S, Hulshoff Pol HE, Schnack HG, Buitelaar JK, Steenhuis MP, Minderaa RB, et al. Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. J. Am. Acad. Child Adolesc. Psych. 2004;43(3):332–340
  15. Duvernoy HM. The Human Brain: Surface, Three-Dimensional Sectional Anatomy and MR1. Vienna: Springer-Verlag; 1991;
  16. Edelbrock C. Problems and issues in using rating scales to assess child personality and psychopathology. Sch. Psychol. Rev. 1983;12:293–299
  17. Filipek PA, Semrud-Clikerman M, Steingard RJ, Renshaw PF, Kennedy DN, Biederman J. Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls. Neurology. 1997;48:89–601
  18. Goyette CH, Conners CK, Ulrich RF. Normative data on revised Conners parent and teacher rating scales. J. Abnorm. Child Psychol. 1978;6(2):221–236
  19. Hakala M, Karlsson H, Kurki T, Aalto S, Koponen S, Vahlberg T, et al. Volumes of the caudate nuclei in women with somatization disorder and healthy women. Psychiatry Res.: Neuroimaging. 2004;131(1):71–78
  20. Hill DE, Yeo RA, Campbell RA, Hart B, Vigil J, Brooks W. Neuropsychology. 2003;17(3):496–506
  21. Hynd GW, Hern KL, Novey ES, Eliopulos D, Marshall R, Gonzalez JJ. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. J. Child Neurol. 1993;8:339–347
  22. Pineda DA, Restrepo MA, Sarmiento RJ, Gutierrez JE, Vargas SA, Quiroz YT, et al. Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention-deficit hyperactivity disorder. J. Child Neurol. 2002;17(2):97–105
  23. Pueyo R, Mañeru C, Vendrell P, Mataró M, Estévez-González A, García-Sánchez C, et al. Trastornos por déficit de atención con hiperactividad. Asimetrías cerebrales observadas en resonancia magnética. Rev. Neurol. 2000;30:920–925
  24. Richfield E, Twyman R, Berent S. Neurological syndrome following bilateral damage to the head of the caudate nuclei. Ann. Neurol. 1987;22(6):768–771
  25. Schrimsher GW, Billingsley RL, Jackson EF, Moore BD. Caudate nucleus volume asymmetry predicts attention-deficit hyperactivity disorder (ADHD) symptomatology in children. J. Child Neurol. 2002;17:877–884
  26. Seger CA, Cincotta CM. The roles of the caudate nucleus in human classification learning. J. Neurosci. 2005;25(11):2941–2951
  27. Semrud-Clikeman M, Steingard RJ, Filipeck P, Biederman J, Bekken K, Renshaw PF. Using MRI to examine brain–behavior relationships in males with attention deficit disorder with hyperactivity. J. Am. Acad. Child Adolesc. Psych. 2000;39(4):477–484
  28. Sergeant J. The cognitive Posner MI, Peterson SE. The attention system of the human brain. Annu. Rev. Neurosci. 1990;13:25–42
  29. Swanson JM, Posner M, Cantwell D, Wigal S, Crinella F, Filipek P, et al. Attention-deficit/hyperactive disorder: symptom domains, cognitive processes and neural networks. In:  Parasuramann R editors. The Attentive Brain. Boston: MIT Press; 1998;
  30. Wechsler D. Manual for the Wechsler Intelligence Scale for Children—Revised. New York: The Psychological Corporation; 1974;
  31. Wechsler D. Escala de Inteligencia de Wechsler para niños revisada (WISC-R). Madrid: TEA Ediciones; 1993;

PII: S0925-4927(07)00095-9

doi: 10.1016/j.pscychresns.2007.04.017

Psychiatry Research: Neuroimaging
Volume 163, Issue 3 , Pages 270-278 , 30 August 2008

Article Tools

* Image Usage & Resolution