Psychiatry Research: Neuroimaging
Volume 156, Issue 2 , Pages 151-167 , 15 November 2007

Neuronal correlates of reward and loss in Cluster B personality disorders: A functional magnetic resonance imaging study

Received 6 October 2006 ,Revised 12 March 2007 ,Accepted 8 April 2007.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders, 4th revised edition (DSM-IV). Washington, DC: American Psychiatric Association; 1994;
  2. Ammons RB, Ammons CH. Quick Test. Missoula: Psychological Test Specialists; 1962;
  3. Aron AR, Fletcher PC, Bullmore ET, Sahakian BJ, Robbins TW. Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans. Nature Neuroscience. 2003;6:115–116
  4. Barratt ES. Impulsiveness defined within a systems model of personality. In:  Spielberger EP,  Butcher JN editor. Advances in Personality Assessment. Hillsdale, NJ: Lawrence Erlbaum; 1985;p. 113–132
  5. Bazanis E, Rogers RD, Dowson JH, Taylor P, Meux C, Staley C, et al. Neurocognitive deficits in decision-making and planning of patients with DSM-III-R borderline personality disorder. Psychological Medicine. 2002;32:1395–1405
  6. Becker DF, Grilo CM, Anez LM, Paris M, McGlashan TH. Discriminant efficiency of antisocial and borderline personality disorder criteria in Hispanic men with substance use disorders. Comprehensive Psychiatry. 2005;46:140–146
  7. Berlin HA, Rolls ET, Iversen SD. Borderline personality disorder, impulsivity, and the orbitofrontal cortex. American Journal of Psychiatry. 2005;162:2360–2373
  8. Blair RJR. Advances in neuropsychiatry: neurocognitive models of aggression, the antisocial personality disorders, and psychopathy. Journal of Neurology, Neurosurgery and Psychiatry. 2001;71:727–731
  9. Blair RJ, Peschardt KS, Budhani S, Mitchell DG, Pine DS. The development of psychopathy. Journal of Child Psychology and Psychiatry and Allied Disciplines. 2006;47:262–276
  10. Bouret S, Sara SJ. Network reset: a simplified overarching theory of locus coeruleus noradrenaline function. Trends in Neurosciences. 2005;28:574–582
  11. Breiter HC, Aharon I, Kahneman D, Dale A, Shizgal P. Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron. 2001;30:619–639
  12. Budhani S, Blair RJR. Response reversal and children with psychopathic tendencies: success is a function of salience of contingency change. Journal of Child Psychology and Psychiatry and Allied Disciplines. 2005;46:972–981
  13. Casey BJ, Trainor RJ, Orendi JL, Schubert AB, Nystrom LE, Giedd JN, et al. A developmental functional MRI study of prefrontal activation during performance of a Go–No-Go task. Journal of Cognitive Neuroscience. 1997;9:835–847
  14. Chabrol H, Leichsenring F. Borderline personality organization and psychopathic traits in nonclinical adolescents: relationships of identity diffusion, primitive defense mechanisms and reality testing with callousness and impulsivity traits. Bulletin of the Menninger Clinic. 2006;70:160–170
  15. Chen TJ, Blum K, Mathews D, Fisher L, Schnautz N, Braverman ER, et al. Are dopaminergic genes involved in a predisposition to pathological aggression? Hypothesizing the importance of “super normal controls” in psychiatricgenetic research of complex behavioral disorders. Medical Hypotheses. 2005;65:703–707
  16. Cherek DR, Moeller FG, Schnapp W, Dougherty DM. Studies of violent and non-violent male parolees: I. Laboratory and psychometric measurements of aggression. Biological Psychiatry. 1997;41:514–522
  17. Cherek DR, Moeller FG, Khan-Dawood F, Swann A, Lane SD. Prolactin response to buspirone was reduced in violent compared to nonviolent parolees. Psychopharmacology. 1999;142:144–148
  18. Comings DE, Blum K. Reward deficiency syndrome: genetic aspects of behavioral disorders. Progress in Brain Research. 2000;126:325–341
  19. Damasio AR. Descartes' Error: Emotion, Reason, and the Human Brain. New York: Putnam; 1994;
  20. Damasio AR, Tranel D, Damasio H. Individuals with sociopathic behavior caused by frontal damage fail to respond autonomically to social stimuli. Behavioural Brain Research. 1990;41:81–94
  21. David JT, Cervantes MC, Trosky KA, Salinas JA, Delville Y. A neural network underlying individual differences in emotion and aggression in male golden hamsters. Neuroscience. 2004;126:567–578
  22. Delgado MR, Nystrom LE, Fissell C, Noll DC, Fiez JA. Tracking the hemodynamic responses to reward and punishment in the striatum. Journal of Neurophysiology. 2000;84:3072–3077
  23. Delgado MR, Locke HM, Stenger VA, Fiez JA. Dorsal striatum responses to reward and punishment: effects of valence and magnitude manipulations. Cognitive, Affective & Behavioral Neuroscience. 2003;3:27–38
  24. Dikman Z, Allen JJB. Error monitoring during reward and avoidance learning in high- and low-socialized individuals. Psychophysiology. 2000;37:43–54
  25. Dinn WM, Harris CL. Neurocognitive function in antisocial personality disorder. Psychiatry Research. 2000;97:173–190
  26. Dolan M, Anderson IM. Executive and memory function and its relationship to trait impulsivity and aggression in personality disordered offenders. Journal of Forensic Psychiatry. 2002;13:503–526
  27. Donegan NH, Sanislow CA, Blumberg HP, Fullbright RK, Lacadie C, Skudlarski R, et al. Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation. Biological Psychiatry. 2003;54:1284–1293
  28. Dougherty DM, Bjork JM, Huckabee HC, Moeller FG, Swann AC. Laboratory measures of aggression and impulsivity in women with borderline personality disorder. Psychiatry Research. 1999;85:315–326
  29. Elliott, R., Deakin, B., 2005. Role of the orbitofrontal cortex in reinforcement processing and inhibitory control: evidence from functional magnetic resonance imaging studies in healthy human subjects. International Review of Neurobiology 65, 89–116.
  30. Elliott R, Friston KJ, Dolan RJ. Dissociable neural responses in human reward systems. Journal of Neuroscience. 2000;16:6159–6165
  31. Elliott R, Newman JL, Longe OA, Deakin JF. Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study. Journal of Neuroscience. 2003;23:303–307
  32. Farabaugh A, Ongur D, Fava M, Hamill SK, Burns AM, Alpert J. Personality disorders and the trimensional personality questionnaire factors in major depressive disorder. Journal of Nervous & Mental Disease. 2005;11:747–750
  33. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Personality Disorders (SCID-II). Washington, D.C.: American Psychiatric Press; 1997;
  34. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID I/P). New York: Biometrics Research; 2002;
  35. Genovese CR, Lazar NR, Nichols TE. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. NeuroImage. 2002;15:870–878
  36. Goethals I, Audenaert K, Jacobs F, Eynde F, Bernagie K, Kolindou A, et al. Brain perfusion SPECT in impulsivity-related personality disorders. Behavioural Brain Research. 2005;157:187–192
  37. Goyer PF, Andreason PJ, Semple WE, Clayton AH, King AC, Compton-Toth BA, et al. Positron-emission tomography and personality disorders. Neuropsychopharmacology. 1994;10:21–28
  38. Gray JA. The Psychology of Fear and Stress. London: Weidenfeld and Nicolson; 1987;
  39. Herpertz SC, Dietrich TM, Wenning B, Krings T, Erberich SG, Willmes K, et al. Evidence of abnormal amygdala functioning in borderline personality disorder: a functional MRI study. Biological Psychiatry. 2001;50:292–298
  40. Jensen J, McIntosh AR, Crawley AP, Mikulis DJ, Remington G, Kapur S. Direct activation of the ventral striatum in anticipation of aversive stimuli. Neuron. 2003;40:1251–1257
  41. Knutson B, Cooper JC. Functional magnetic resonance imaging of reward prediction. Current Opinion in Neurology. 2005;18:411–417
  42. Knutson B, Westdorp A, Kaiser E, Hommer D. FMRI visualization of brain activity during a monetary incentive delay task. NeuroImage. 2000;12:20–27
  43. Knutson B, Fong GW, Adams CM, Varner JL, Hommer D. Dissociation of reward anticipation and outcome with event-related fMRI. NeuroReport. 2001;12:3683–3687
  44. Kringelbach ML. The human orbitofrontal cortex: linking reward to hedonic experience. Nature Reviews. Neuroscience. 2005;6:691–702
  45. Kringelbach ML, Rolls ET. The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology. Progress in Neurobiology. 2004;72:341–372
  46. Kringelbach ML, O'Doherty J, Rolls ET, Andrews C. Activation of the human orbitofrontal cortex to a liquid food stimulus is correlated with its subjective pleasantness. Cerebral Cortex. 2003;13:1064–1071
  47. Lapierre D, Braun CM, Hodgins S. Ventral frontal deficits in psychopathy: neuropsychological test findings. Neuropsychologia. 1995;33:139–151
  48. Levesque J, Joanette Y, Mensour B, Beaudoin G, Leroux JM, Bourgouin P, et al. Neural basis of emotional self-regulation in childhood. Neuroscience. 2004;129:361–369
  49. Liddle PF, Kiehl KA, Smith AM. Event-related fMRI study of response inhibition. Human Brain Mapping. 2001;12:100–109
  50. Maggini C, Ampollini P, Marchesi C, Gariboldi S, Cloninger CR. Relationships between Tridimensional Personality Questionnaire Dimensions and DSM-III-R personality traits in Italian adolescents. Comprehensive Psychiatry. 2000;41:426–431
  51. May JC, Delgado MR, Dahl RE, Stenger VA, Ryan ND, Fiez JA, et al. Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents. Biological Psychiatry. 2004;55:359–366
  52. McClure SM, York MK, Montague PR. The neural substrates of reward processing in humans: the modern role of FMRI. Neuroscientist. 2004;10:260–268
  53. Moeller FG, Dougherty DM, Barratt ES, Oderinde V, Mathias CW, Harper RA, et al. Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggression. Drug and Alcohol Dependence. 2002;68:105–111
  54. Mulder RT, Joyce PR, Sullivan PF, Bulik CM, Carter FA. The relationship among three models of personality psychopathology: DSM-III-R personality disorder, TCI scores and DSQ defences. Psychological Medicine. 1999;29:943–951
  55. O'Doherty JP. Reward representations and reward-related learning in the human brain: insights from neuroimaging. Current Opinion in Neurobiology. 2004;14:769–776
  56. O'Doherty J, Rolls ET, Francis S, Bowtell R, McGlone F. Representation of pleasant and aversive taste in the human brain. Journal of Neurophysiology. 2001;85:1315–1321
  57. O'Doherty J, Kringelbach ML, Rolls ET, Hornak J, Andrews C. Abstract reward and punishment representations in the human orbitofrontal cortex. Nature Neuroscience. 2001;4:95–102
  58. O'Doherty JP, Deichmann R, Critchley HD, Dolan RJ. Neural responses during anticipation of a primary taste reward. Neuron. 2002;33:815–826
  59. O'Doherty J, Critchley H, Deichmann R, Dolan RJ. Dissociating valence of outcome from behavioral control in human orbital and ventral prefrontal cortices. Journal of Neuroscience. 2003;23:7931–7939
  60. Paris J. Antisocial and borderline personality disorders: two separate diagnoses or two aspects of the same psychopathology?. Comprehensive Psychiatry. 1997;38:237–242
  61. Petry NM. Discounting of delayed rewards in substance abusers: relationship to antisocial personality disorder. Psychopharmacology. 2002;162:425–432
  62. Phelps, E.A., 2006. Emotion and cognition: insights from studies of the human amygdala. Annual Review of Psychology 57, 27–53.
  63. Raine A, Lencz T, Bihrle S, LaCasse L, Colletti P. Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Archives of General Psychiatry. 2000;57:119–127
  64. Remijnse PL, Nielen MM, Uylings HB, Veltman DJ. Neural correlates of a reversal learning task with an affectively neutral baseline: an event-related fMRI study. NeuroImage. 2005;26:609–618
  65. Rogers RD. Neuropsychological investigations of the impulsive personality disorder. Psychological Medicine. 2003;33:1335–1340
  66. Rolls ET. Taste and olfactory processing in the brain and its relation to the control of eating. Critical Reviews in Neurobiology. 1997;11:263–287
  67. Saver JL, Damasio AR. Preserved access and processing of social knowledge in a patient with acquired sociopathy due to ventromedial frontal damage. Neuropsychologia. 1991;29:1241–1249
  68. Scerbo A, Raine A, O'Brien M, Chan CJ, Rhee C, Smiley N. Reward dominance and passive avoidance learning in adolescent psychopaths. Journal of Abnormal Child Psychology. 1990;18:451–463
  69. Schultz W. Dopamine neurons and their role in reward mechanisms. Current Opinion in Neurobiology. 1997;7:191–197
  70. Schultz W. Multiple reward signals in the brain. Nature Reviews. Neuroscience. 2000;1:199–207
  71. Sheehan DV, Lecrubier Y, Harnett-Sheehan K, Janavs J, Weiller E, Bonara LI, et al. The validity of the Mini International Neuropyschiatric Interview (MINI) according to the SCID-P and its reliability. European Psychiatry. 1997;12:224–231
  72. Talairach J, Tournoux P. Coplanar Stereotactic Atlas of the Human Brain. Stuttgart: Georg Thieme Verlag; 1988;
  73. Tanaka SC, Doya K, Okada G, Ueda K, Okamoto Y, Yamawaki S. Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops. Nature Neuroscience. 2004;7:887–893
  74. Völlm B, Richardson P, Stirling J, Elliott R, Dolan M, Chaudhry I, et al. Neurobiological substrates of antisocial and borderline personality disorder: preliminary results of a functional fMRI study. Criminal Behaviour and Mental Health. 2004;14:39–54
  75. Zalla T, Koechlin E, Pietrini P, Basso G, Aquino P, Sirigu A, et al. Differential amygdala responses to winning and losing: a functional magnetic resonance imaging study in humans. European Journal of Neuroscience. 2000;12:1764–1770
  76. Zanarini MC, Frankenburg FR, Dubo ED, Sickel AE, Trikha A, Levin A, et al. Axis II comorbidity of borderline personality disorder. Comprehensive Psychiatry. 1998;39:296–302

PII: S0925-4927(07)00088-1

doi: 10.1016/j.pscychresns.2007.04.008

Psychiatry Research: Neuroimaging
Volume 156, Issue 2 , Pages 151-167 , 15 November 2007

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