Psychiatry Research: Neuroimaging
Volume 156, Issue 2 , Pages 117-127 , 15 November 2007

Atypical involvement of frontostriatal systems during sensorimotor control in autism

  • Yukari Takarae

      Affiliations

    • Department of Psychiatry (MC 913), University of Illinois at Chicago, 912 S. Wood St., Suite 235, Chicago, IL 60612-7327, USA
    • ,
  • Nancy J. Minshew

      Affiliations

    • Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    • ,
  • Beatriz Luna

      Affiliations

    • Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    • ,
  • John A. Sweeney

      Affiliations

    • Department of Psychiatry (MC 913), University of Illinois at Chicago, 912 S. Wood St., Suite 235, Chicago, IL 60612-7327, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 312 413 9205; fax: +1 312 413 8837.

Received 21 January 2006 ,Revised 18 March 2007 ,Accepted 21 March 2007.

References 

  1. Allen G, Müller RA, Courchesne E. Cerebellar function in autism: functional magnetic resonance image activation during a simple motor task. Biological Psychiatry. 2004;56(4):269–278
  2. Bailey A, Luthert P, Dean A, Montgomery MRM, Lantos S. A clinicopathological study of autism. Brain. 1998;121:889–905
  3. Belmonte MK, Yurgelun-Todd DA. Functional anatomy of impaired selective attention and compensatory processing in autism. Cognitive Brain Research. 2003;17(3):651–664
  4. Brown MR, DeSouza JF, Goltz HC, Ford K, Menon RS, Goodale MA, et al. Comparison of memory- and visually-guided saccades using event-related fMRI. Journal of Neurophysiology. 2004;91(2):873–889
  5. Casanova MF, Buxhoeveden DP, Switala AE, Roy E. Minicolumnar pathology in autism. Neurology. 2002;58(3):428–432
  6. Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, et al. Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology. 2001;57(2):245–254
  7. Cox RW. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Computers and Biomedical Research. 1996;29:162–173
  8. DeSouza JF, Menon RS, Everling S. Preparatory set associated with pro-saccades and anti-saccades in humans investigated with event-related fMRI. Journal of Neurophysiology. 2003;89(2):1016–1023
  9. Eddy WF, Fitzgerald M, Genovese CR, Mockus A, Noll DC. Functional image analysis software-computational olio. In:  Prat A editors. Proceedings in Computational Statistics. Heidelberg: Physica-Verlag; 1996;p. 39–49
  10. Filipek PA, Richelme C, Kennedy DN, Rademacher J, Pitcher DA, Zidel S, et al. Morphometric analysis of the brain in developmental language disorders and autism. Annals of Neurology. 1992;32:475
  11. Floyer-Lea A, Matthews PM. Changing brain networks for visuomotor control with increased movement automaticity. Journal of Neurophysiology. 2004;92(4):2405–2412
  12. Forman SD, Cohen JD, Fitzgerald M, Eddy WF, Mintun MA, Noll DC. Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold. Magnetic Resonance Medicine. 1995;33:636–647
  13. Goldberg MC, Lasker AG, Zee DS, Garth E, Tien A, Landa RJ. Deficits in the initiation of eye movements in the absence of a visual target in adolescents with high functioning autism. Neuropsychologia. 2002;40:2039–2049
  14. Haist F, Adamo M, Westerfield M, Courchesne E, Townsend J. The functional neuroanatomy of spatial attention in autism spectrum disorder. Developmental Neuropsychology. 2005;27(3):425–458
  15. Hendry J, Devito T, Gelman N, Densmore M, Rajakumar N, Pavlosky W, et al. White matter abnormalities in autism detected through transverse relaxation time imaging. NeuroImage. 2006;29(4):1049–1057
  16. Herbert MR, Ziegler DA, Makris N, Filipek PA, Kemper TL, Normandin JJ, et al. Localization of white matter volume increase in autism and developmental language disorder. Annals of Neurology. 2004;55(4):530–540
  17. Hill EL. Executive dysfunction in autism. Trends in Cognitive Science. 2004;8(1):26–32
  18. Just MA, Cherkassky VL, Keller TA, Minshew NJ. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain. 2004;127:1811–1821
  19. Keedy SK, Ebens C, Keshavan MS, Sweeney JA. FMRI studies of eye movements in first-episode schizophrenia: smooth pursuit, visually guided saccades, and the oculomotor delayed response task. Psychiatry Research. Neuroimaging. 2006;146:199–211
  20. Keller EL, Heinen SJ. Generation of smooth-pursuit eye movements: neuronal mechanisms and pathways. Neuroscience Research. 1991;11:79–107
  21. Kemper TL, Bauman M. Neuropathology of infantile autism. Journal of Neuropathology and Experimental Neurology. 1998;57(7):645–652
  22. Krauzlis RJ. Recasting the smooth pursuit eye movement system. Journal of Neurophysiology. 2004;91(2):591–603
  23. Kwong KK, Belliveau JW, Chesler DA, Goldberg IE, Weisskoff RM, Poncelet BP, et al Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proceedings of the National Academy of Sciences of the United States of America. 1992;89(12):5675–5679
  24. Lazar NA, Luna B, Sweeney JA, Eddy WF. Combining brains: a survey of methods for statistical pooling of information. NeuroImage. 2002;16(2):538–550
  25. Lord C, Rutter M, Le Couteur A. Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders. 1994;24(5):659–685
  26. Lord C, Risi S, Lambrecht L, Cook EH, Leventhal BL, DiLavore PC, et al. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders. 2000;30(3):205–223
  27. Luna B, Thulborn KR, Strojwas MH, McCurtain BJ, Berman RA, Genovese CR, et al. Dorsal cortical regions subserving visually-guided saccades in humans: an fMRI study. Cerebral Cortex. 1998;8:40–47
  28. Luna B, Minshew NJ, Garver K, Lazar NA, Thulborn KR, Eddy WF, et al. Neocortical system abnormalities in autism: an fMRI study of spatial working memory. Neurology. 2002;59(6):834–840
  29. Luna B, Doll SK, Hegedus SJ, Minshew NJ, Sweeney JA. Maturation of executive function in autism. Biological Psychiatry. 2007;61(4):474–481
  30. Minshew NJ, Goldstein G, Siegel DJ. Neuropsychologic functioning in autism: profile of a complex information processing disorder. Journal of the International Neuropsychological Society. 1997;3:303–316
  31. Minshew NJ, Luna B, Sweeney JA. Oculomotor evidence for neocortical systems but not cerebellar dysfunction in autism. Neurology. 1999;52(5):917–922
  32. Minshew NJ, Sung K, Jones BL, Furman JM. Underdevelopment of the postural control system in autism. Neurology. 2004;63(11):2056–2061
  33. Molloy CA, Dietrich KN, Bhattacharya A. Postural stability in children with autism spectrum disorder. Journal of Autism and Developmental Disorders. 2003;33(6):643–652
  34. Mostofsky SH, Goldberg MC, Landa RJ, Denckla MB. Evidence for a deficit in procedural learning in children and adolescents with autism: implications for cerebellar contribution. Journal of the International Neuropsychological Society. 2000;6(7):752–759
  35. Müller RA, Pierce K, Ambrose JB, Allen G, Courchesne E. Atypical patterns of cerebral motor activation in autism: a functional magnetic resonance study. Biological Psychiatry. 2001;49(8):665–676
  36. Munoz DP, Broughton J, Goldring J, Armstrong I. Age-related performance of human subjects on saccadic eye movement tasks. Experimental Brain Research. 1998;121(4):391–400
  37. Nitschke MF, Binkofski F, Buccino G, Posse S, Erdmann C, Kompf D, et al. Activation of cerebellar hemispheres in spatial memorization of saccadic eye movements: an fMRI study. Human Brain Mapping. 2004;22(2):155–164
  38. Picard N, Strick PL. Imaging the premotor areas. Current Opinion in Neurobiology. 2001;11(6):663–672
  39. Pierrot-Deseilligny C, Ploner CJ, Muri RM, Gaymard B, Rivaud-Pechoux S. Effects of cortical lesions on saccadic eye movements in humans. Annals of New York Academy of Science. 2002;956:216–229
  40. Rinehart NJ, Bradshaw JL, Brereton AV, Tonge BJ. Movement preparation in high-functioning autism and Asperger disorder: a serial choice reaction time task involving motor reprogramming. Journal of Autism and Developmental Disorders. 2001;31(1):79–88
  41. Rosano C, Krisky CM, Welling JS, Eddy WF, Luna B, Thulborn KR, et al. Pursuit and saccadic eye movement subregions in human frontal eye field: a high-resolution fMRI investigation. Cerebral Cortex. 2002;12(2):107–115
  42. Sabatini U, Boulanouar K, Fabre N, Martin F, Carel C, Colonnese C, et al. Cortical motor reorganization in akinetic patients with Parkinson's disease: a functional MRI study. Brain. 2000;123:394–403
  43. Simo LS, Krisky CM, Sweeney JA. Functional neuroanatomy of anticipatory behavior: dissociation between sensory-driven and memory-driven systems. Cerebral Cortex. 2005;15(2):1982–1991
  44. Sparks BF, Friedman SD, Shaw DW, Aylward EH, Echelard D, Artru AA, et al. Brain structural abnormalities in young children with autism spectrum disorder. Neurology. 2002;59(2):184–192
  45. Sweeney JA, Mintun MA, Kwee S, Wiseman MB, Brown DL, Rosenberg DR, et al. Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. Journal of Neurophysiology. 1996;75(1):454–468
  46. Takarae Y, Minshew NJ, Luna B, Krisky CM, Sweeney JA. Pursuit eye movement deficits in autism. Brain. 2004;127:2584–2594
  47. Takarae Y, Minshew NJ, Luna B, Sweeney JA. Oculomotor abnormalities parallel cerebellar histopathology in autism. Journal of Neurology, Neurosurgery and Psychiatry. 2004;75(9):1359–1361
  48. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York: Thieme Medical Publishers; 1988;
  49. van der Geest JN, Kemner C, Camfferman G, Verbaten MN, van Engeland H. Eye movements, visual attention, and autism: a saccadic reaction time study using the gap and overlap paradigm. Biological Psychiatry. 2001;50(8):614–619
  50. Wessel K, Zeffiro T, Lou JS, Toro C, Hallett M. Regional cerebral blood flow during a self-paced sequential finger opposition task in patients with cerebellar degeneration. Brain. 1995;118:379–393

PII: S0925-4927(07)00067-4

doi: 10.1016/j.pscychresns.2007.03.008

Psychiatry Research: Neuroimaging
Volume 156, Issue 2 , Pages 117-127 , 15 November 2007

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