Psychiatry Research: Neuroimaging
Volume 154, Issue 2 , Pages 103-114 , 28 February 2007

Dissociating the effects of Sternberg working memory demands in prefrontal cortex

  • Mario Altamura

      Affiliations

    • Department of Biomedical Sciences, Psychiatry Unit, University of Foggia, Italy
    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
    • Corresponding Author InformationCorresponding author. Department of Biomedical Sciences, Psychiatry Unit, University of Foggia, Italy. Tel./fax: +39 01139/0881 732285.
  • ,
  • Brita Elvevåg

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
  • ,
  • Giuseppe Blasi

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
    • Department of Neurology and Psychiatry, University of Bari, Italy
  • ,
  • Alessandro Bertolino

      Affiliations

    • Department of Neurology and Psychiatry, University of Bari, Italy
    • Department of Neuroradiology, IRCCSS “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Italy
  • ,
  • Joseph H. Callicott

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
  • ,
  • Daniel R. Weinberger

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
  • ,
  • Venkata S. Mattay

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA
  • ,
  • Terry E. Goldberg

      Affiliations

    • Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda MD, USA

Received 14 May 2006 ,Revised 20 August 2006 ,Accepted 22 August 2006.

References 

  1. Awh E, Jonides J, Smith EE, Schumacher EH, Koeppe RA, Katz S. Dissociation of storage and rehearsal in verbal working memory. Psychological Science. 1996;7:25–31
  2. Baddeley A. Working Memory. Oxford, UK: Clarendon Press/Oxford University Press; 1986;
  3. Barch DM, Braver TS, Nystrom LE, Forman SD, Noll DC, Cohen JD. Dissociating working memory from task difficulty in human prefrontal cortex. Neuropsychologia. 1997;35:1373–1380
  4. Bedwell JS, Horner MD, Yamanka K, Li X, Myrick H, Nahas Z, et al. Fuctional neuroanatomy of subcomponent cognitive processes involved in verbal working memory. International Journal of Neuroscience. 2005;115:1017–1032
  5. Braver TS, Cohen JD, Nystrom LE, Jonides J, Smith EE, Noll DC. A parametric study of prefrontal cortex involvement in human working memory. NeuroImage. 1997;5:49–62
  6. Bunge SA, Ochsner KN, Desmond JE, Glover GH, Gabrieli JD. Prefrontal regions involved in keeping information in and out of mind. Brain. 2001;124:2074–2086
  7. Cairo TA, Liddle PF, Woodward TS, Ngan ET. The influence of working memory load on phase specific patterns of cortical activity. Brain Research. Cognitive Brain Research. 2004;21:377–387
  8. Cohen JD, Perlstein WM, Braver TS, Nystrom LE, Noll DC, Jonides J, et al. Temporal dynamics of brain activation during a working memory task. Nature. 1997;368:604–607
  9. Collette F, Salmon E, Van der Linden M, Chicherio C, Belleville S, Degueldre C, et al. Regional brain activity during tasks devoted to the central executive of working memory. Brain Research. Cognitive Brain Research. 1999;7:411–417
  10. Courtney SM, Ungerleider LG, Keil K, Haxby JV. Transient and sustained activity in a distributed neural system for working memory. Nature. 1997;386:608–611
  11. Courtney SM, Petit L, Maisog JM, Ungerleider LG, Haxby JV. An area specialized for spatial working memory in human frontal cortex. Science. 1998;279:1347–1351
  12. Curtis CE, D'Esposito M. Persistent activity in the prefrontal cortex during working memory. Trends in Cognitive Sciences. 2003;7:415–423
  13. D'Esposito M, Aguirre GK, Zarahn E, Ballard D, Shin RK, Lease J. Functional MRI studies of spatial and nonspatial working memory. Brain Research. Cognitive Brain Research. 1998;7:1–13
  14. D'Esposito M, Postle BR, Ballard D, Lease J. Maintenance versus manipulation of information held in working memory: an event-related fMRI study. Brain and Cognition. 1999;41:66–86
  15. D'Esposito M, Postle BR, Rypma B. Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies. Experimental Brain Research. 2000;133:3–11
  16. Druzgal TJ, D'Esposito M. Dissecting contributions of prefrontal cortex and fusiform face area to face working memory. Journal of Cognitive Neuroscience. 2003;15:771–784
  17. Elliott R, Dolan RJ. Differential neural responses during performance of matching and nonmatching to sample tasks at two delay intervals. Journal of Neuroscience. 1999;19:5066–5073
  18. Fiez JA, Raife EA, Balota DA, Schwarz JP, Raichle ME, Petersen SE. A positron emission tomography study of the short-term maintenance of verbal information. Journal of Neuroscience. 1996;16:808–822
  19. Fletcher PC, Henson RN. Frontal lobes and human memory: insights from functional neuroimaging. Brain. 2001;124:849–881
  20. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. NeuroImage. 2002;15:870–878
  21. Glahn DC, Kim J, Cohen MS, Poutanen VP, Therman S, Bava S, et al. Maintenance and manipulation in spatial working memory: dissociations in prefrontal cortex. NeuroImage. 2002;17:201–213
  22. Goldman-Rakic PS. The physiological approach: functional architecture of working memory and disordered cognition in schizophrenia. Biological Psychiatry. 1999;46:650–661
  23. Grady CL, McIntosh AR, Bookstein F, Horowitz B, Rapoport SI, Haxby JV. Age-related changes in regional cerebral blood flow during working memory for faces. NeuroImage. 1998;8:409–425
  24. Habeck C, Rakitin BC, Moeller J, Scarmeas N, Zarahn E, Brown T, et al. An event-related fMRI study of the neural networks underlying the encoding, maintenance, and retrieval phase in a delayed-match-to-sample task. Brain Research. Cognitive Brain Research. 2005;23:207–220
  25. Hartley AA, Speer NK. Locating and fractioning working memory using functional neuroimaging: storage, maintenance and executive functions. Microscopy Research and Technique. 2000;51:43–53
  26. Haxby JV, Ungerleider LG, Horwitz B, Rapoport SI, Grady CL. Hemispheric differences in neural system for face working memory: A PET-rCBF Study. Human Brain Mapping. 1995;3:68–82
  27. Haxby JV, Petit L, Ungerleider LG, Courtney SM. Distinguishing the functional roles of multiple regions in distributed neural systems for visual working memory. NeuroImage. 2000;11:380–391
  28. Honey GD, Fu CH, Kim J, Brammer MJ, Croudace TJ, Suckling J, et al. Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging data. Neuroimage. 2002;17:573–582
  29. Leung HC, Gore JC, Goldman-Rakic PS. Sustained mnemonic response in the human middle frontal gyrus during on-line storage of spatial memoranda. Journal of Cognitive Neuroscience. 2002;14:659–671
  30. Leung HC, Seelig D, Gore JC. The effect of memory load on cortical activity in the spatial working memory circuit. Cognitive, Affective and Behavioral Neuroscience. 2004;4:553–563
  31. Jansma JM, Ramsey NF, Coppola R, Kahn RS. Specific versus nonspecific brain activity in a parametric N-back task. NeuroImage. 2000;12:688–697
  32. Jansma JM, Ramsey NF, Slagter HA, Kahn RS. Functional anatomical correlates of controlled and automatic processing. Journal of Cognitive Neuroscience. 2001;13:730–743
  33. Jonides J, Schumacher EH, Smith EE, Lauber EJ, Ahw E, Minoshima S, et al. Verbal working memory load affects regional brain activation as measured by PET. Journal of Cognitive Neuroscience. 1997;9:462–475
  34. Kruggel F, Zysset S, von Cramon DY. Nonlinear regression of functional MRI data: an item recognition task study. NeuroImage. 2000;12:173–183
  35. Manoach DS, Schlaug G, Siewert B, Darby DG, Bly BM, Benfield A, et al. Prefrontal cortex fMRI signal changes are correlated with working memory load. Neuroreport. 1997;8:545–549
  36. Manoach DS, Greve DN, Lindgren KA, Dale AM. Identifying regional activity associated with temporally separated components of working memory using event-related functional MRI. NeuroImage. 2003;20:1670–1684
  37. McCarthy G, Puce A, Constable RT, Krystal JH, Gore JC, Goldman-Rakic P. Activation of human prefrontal cortex during spatial and nonspatial working memory tasks measured by functional MRI. Cerebral Cortex. 1996;6:600–611
  38. McIntosh AR, Grady CL, Haxby JV, Ungerleider LG, Horowitz B. Changes in limbic and prefrontal interactions in a working memory task for faces. Cerebral Cortex. 1996;6:571–584
  39. Narayanan NS, Prabhakaran V, Bunge S, Christoff K, Fine EM, Gabrieli JDE. The role of the prefrontal cortex in the maintenance of verbal working memory: an event-related fMRI analysis. Neuropsychology. 2005;19:223–232
  40. Paulesu E, Frith CD, Frackowiak RS. The neural correlates of the verbal component of working memory. Nature. 1993;25:342–345
  41. Petit L, Courtney SM, Ungerleider L, Haxby JV. Sustained activity in the medial wall during working memory delays. Journal of Neuroscience. 1998;18:9429–9437
  42. Postle BR, Berger JS, D'Esposito M. Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance. Proceedings of the National Academy of Sciences of the United States of America. 1999;26:12959–12964
  43. Rypma B. Factors controlling neural activity during delayed-response task performance: testing a memory organization hypothesis of prefrontal function. Neuroscience. 2006;139:223–235
  44. Rypma B, D'Esposito M. The roles of prefrontal brain regions in components of working memory: effects of memory load and individual differences. Proceedings of the National Academy of Sciences of the United States of America. 1999;25:6558–6563
  45. Rypma B, D'Esposito M. Isolating the neural mechanisms of age-related changes in human working memory. Nature Neuroscience. 2000;3:509–515
  46. Rypma B, Prabhakaran V, Desmond JE, Glover GH, Gabrieli JD. Load-dependent roles of frontal brain regions in the maintenance of working memory. NeuroImage. 1999;9:216–226
  47. Rypma B, Berger JS, D'Esposito M. The influence of working-memory demand and subject performance on prefrontal cortical activity. Journal of Cognitive Neuroscience. 2002;1:721–731
  48. Smith EE, Jonides J, Koeppe RA. Dissociating verbal and spatial working memory using PET. Cerebral Cortex. 1996;6:11–20
  49. Smith EE, Jonides J, Marshuetz C, Koeppe RA. Components of verbal working memory: evidence from neuroimaging. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:876–882
  50. Sternberg S. High speed scanning in human memory. Science. 1966;153:625–654
  51. Veltman DJ, Rombouts SA, Dolan RJ. Maintenance versus manipulation in verbal working memory revisited: an fMRI study. NeuroImage. 2003;18:247–256
  52. Zarahn E, Aguirre GK, D'Esposito M. Temporal isolation of the neural correlates of spatial mnemonic processing with fMRI. Brain Research. Cognitive Brain Research. 1999;7:255–268
  53. Zarahn E, Rakitin B, Abela D, Flynn J, Stern Y. Positive evidence against human hippocampal involvement in working memory maintenance of familiar stimuli. Cerebral Cortex. 2005;15:303–316

PII: S0925-4927(06)00127-2

doi: 10.1016/j.pscychresns.2006.08.002

Psychiatry Research: Neuroimaging
Volume 154, Issue 2 , Pages 103-114 , 28 February 2007