Psychiatry Research: Neuroimaging
Volume 148, Issue 1 , Pages 61-66 , 22 November 2006

Early detection of schizophrenia by diffusion weighted imaging

  • Lynn E. DeLisi

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • The New York University School of Medicine, Department of Psychiatry, 650 First Avenue, New York, NY 10016, USA
    • Corresponding Author InformationCorresponding author. The Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA. Tel.: +1 845 398 5471; fax: +1 845 398 5472.
    • ,
  • Kamila U. Szulc

      Affiliations

    • The New York University School of Medicine, Department of Psychiatry, 650 First Avenue, New York, NY 10016, USA
    • ,
  • Hilary Bertisch

      Affiliations

    • The New York University School of Medicine, Department of Psychiatry, 650 First Avenue, New York, NY 10016, USA
    • ,
  • Magda Majcher

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • ,
  • Kyle Brown

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • ,
  • Arthika Bappal

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • ,
  • Craig A. Branch

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    • ,
  • Babak A. Ardekani

      Affiliations

    • The Nathan S. Kline Institute for Psychiatric Research, Department of Medical Physics, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    • The New York University School of Medicine, Department of Psychiatry, 650 First Avenue, New York, NY 10016, USA

Received 12 January 2006 ,Revised 7 April 2006 ,Accepted 26 April 2006.

References 

  1. Ardekani BA, Bappal A, D'Angelo D, Ashtari M, Lencz T, Szeszko PR, et al. Brain morphometry using diffusion weighted MRI: application to schizophrenia. NeuroReport. 2005;16:1455–1459
  2. Basser PJ. Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. NMR in Biomedicine. 1995;8:333–344
  3. DeLisi LE. Defining the course of brain structural growth and plasticity in schizophrenia. Psychiatry Research: Neuroimaging. 1999;92(1):1–9
  4. DeLisi LE, Sherrington R, Shaw S, Nanthakumar B, Shields G, Smith AB, et al. A genome-wide scan of 382 affected sibling-pairs with schizophrenia suggests linkage to chromosomes 2cen and 10p. American Journal of Psychiatry. 2002;159:803–812
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  6. Job DE, Whalley HC, Johnstone EC, Lawrie SM. Grey matter changes over time in high risk subjects developing schizophrenia. NeuroImage. 2005;25(4):1023–1030
  7. Jacobi W, Winkler H. Encephalographische studien an chronische schizophrenen. Archiv für Psychiatrie und Nervenkrankheiten. 1927;81:299–332
  8. Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet. 1976;2(7992):924–926
  9. Lawrie SM, Whalley HC, Abukmeil SS, Kestelman JN, Miller P, Best JJ, et al. Temporal lobe volume changes in people at high risk of schizophrenia with psychotic symptoms. British Journal of Psychiatry. 2002;181:138–143
  10. Meier C, Dreher W, Leibfritz D. Diffusion in compartmental systems. I. A comparison of an analytical model with simulations. Magnetic Resonance in Medicine. 2003;50(3):500–509
  11. Pantelis C, Velakoulis D, McGorry PD, Wood SJ, Suckling J, Phillips LJ, et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet. 2003;361(9354):281–288
  12. Shenton ME, Dickey CC, Frumin M, McCarley RW. A review of MRI findings in schizophrenia. Schizophrenia Research. 2001;49(1–2):1–52
  13. Szafer A, Zhong J, Anderson AW, Gore JC. Diffusion-weighted imaging in tissues: theoretical models. NMR in Biomedicine. 1995;7–8:289–296
  14. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York: Thieme Medical Publishers, Inc.; 1988;
  15. Weinberger DR, Torrey EF, Neophytides AN, Wyatt RJ. Lateral cerebral ventricular enlargement in chronic schizophrenia. Archives of General Psychiatry. 1979;36(7):735–739
  16. Weinberger DR, Torrey EF, Neophytides AN, Wyatt RJ. Structural abnormalities in the cerebral cortex of chronic schizophrenic patients. Archives of General Psychiatry. 1979;36(9):935–939

PII: S0925-4927(06)00082-5

doi: 10.1016/j.pscychresns.2006.04.010

Psychiatry Research: Neuroimaging
Volume 148, Issue 1 , Pages 61-66 , 22 November 2006

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