Psychiatry Research: Neuroimaging
Volume 154, Issue 1 , Pages 59-68 , 15 January 2007

Volumetric reduction of the corpus callosum in Alzheimer's disease in vivo as assessed with voxel-based morphometry

  • Tiffany M. Chaim

      Affiliations

    • Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
    • ,
  • Fábio L.S. Duran

      Affiliations

    • Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
    • ,
  • Ricardo R. Uchida

      Affiliations

    • Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
    • Department of Psychiatry, Santa Casa Medical School, São Paulo, Brazil
    • ,
  • Cintia A.M. Périco

      Affiliations

    • Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
    • ,
  • Claudio C. de Castro

      Affiliations

    • Department of Radiology, University of São Paulo Medical School, São Paulo, Brazil
    • ,
  • Geraldo F. Busatto

      Affiliations

    • Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. Rua Ovídio Pires Campos, s/n-CEP 05403-010, São Paulo, Brazil. Tel./fax: +55 11 30643567.

Received 20 October 2005 ,Revised 11 March 2006 ,Accepted 2 April 2006.

References 

  1. Ashburner J, Friston KJ. Voxel-based morphometry—the methods. NeuroImage. 2000;11:805–821
  2. Baron JC, Chetelat G, Desgranges B, Perchey G, Landeau B, de la Sayette V, et al. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. NeuroImage. 2001;14:298–309
  3. Biegon A, Eberling JL, Richardson BC, Roos MS, Wong ST, Reed BR, et al. Human corpus callosum in aging and Alzheimer's disease: a magnetic resonance imaging study. Neurobiology of Aging. 1994;15:393–397
  4. Black SE, Moffat SD, Yu DC, Parker J, Stanchev P, Bronskill M. Callosal atrophy correlates with temporal lobe volume and mental status in Alzheimer's disease. Canadian Journal of Neurological Sciences. 2000;27:204–209
  5. Blackwood DHR, Glabus MF, Dunan J, O'Carroll RE, Muir WJ, Ebmeier KP. Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia. Correlations with memory and P300. British Journal of Psychiatry. 1999;175:357–366
  6. Bookstein FL. Landmark methods for forms without landmarks: morphometrics of group differences in outline shape. Medical Image Analysis. 1997;1:225–243
  7. Bookstein FL. “Voxel-based morphometry” should not be used with imperfectly registered images. NeuroImage. 2001;14:1454–1462
  8. Bozzali M, Falini A, Franceschi M, Cercignani M, Zuffi M, Scotti G, et al. White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging. Journal of Neurology, Neurosurgery and Psychiatry. 2002;72:742–746
  9. Brett M, Johnsrude IS, Owen AM. The problem of functional localization in the human brain. Nature Reviews. Neuroscience. 2002;3:243–249
  10. Busatto GF, Garrido GEJ, Almeida OP, Castro CC, Camargo CHP, Cid CG, et al. A voxel-based morphometry study of temporal lobe gray matter reductions in Alzheimer's disease. Neurobiology of Aging. 2003;24:221–231
  11. Davatzikos C, Vaillant M, Resnick SM, Prince JL, Letovsky S, Bryan RN. A computerized approach for morphological analysis of the corpus callosum. Journal of Computer Assisted Tomography. 1996;20:88–97
  12. DeQuardo JR, Keshavan MS, Bookstein FL, Bagwell WW, Green WD, Sweeney JA, et al. Landmark-based morphometric analysis of first-episode schizophrenia. Biological Psychiatry. 1999;45:1321–1328
  13. Doubleb KL, Halliday GM, Krill JJ, Harasty JA, Cullen K, Brooks WS, et al. Topography of brain atrophy during normal aging and Alzheimer's disease. Neurobioly of Aging. 1996;17:513–521
  14. Dougherty DD, Shin LM, Alpert NM, Pitman RK, Orr SP, Lasko M, et al. Anger in healthy men: a PET study using script-driven imagery. Biological Psychiatry. 1999;46:466–472
  15. Fellgiebel A, Wille P, Muller MJ, Winterer G, Scheurich A, Vucurevic G, et al. Ultrastrucutural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study. Dementia and Geriatric Cognitive Disorders. 2004;18:101–108
  16. Folstein MF, Folstein SE, McHugh PR. “Mini-Mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research. 1975;12:189–198
  17. Friston KJ, Holmes AP, Worsley K, Poline JB, Frith CD, Frackowiak RSJ. Statistic parametric maps in functional imaging: A general linear approach. Human Brain Mapping. 1995;2:189–210
  18. Fuld PA, Masur DM, Blau AD, Crystal H, Aronson MK. Object-memory evaluation for prospective detection of dementia in normal functioning elderly: predictive and normative data. Journal of Clinical and Experimental Neuropsychology. 1990;12:520–528
  19. Galton CJ, Patterson K, Graham K, Lambon-Ralph MA, Williams G, Antoun N, et al. Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia. Neurology. 2001;57:216–225
  20. Garrido GE, Furuie SS, Buchpiguel CA, Bottino CN, Almeida OP, Cid CG, et al. Relation between medial temporal atrophy in functional brain activity during memory processing in Alzheimer's Disease: a combined in MRI and SPECT study. Journal of Neurology, Neurosurgery and Psychiatry. 2002;73:508–516
  21. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage. 2001;14:21–36
  22. Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, et al. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. NeuroImage. 2002;17:29–46
  23. Gootjes L, Teipel SJ, Zebur Y, Schwarz R, Leinsinger G, Scheltens P, et al. Regiona distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging. Dementia and Geriatric Cognitive Disorders. 2004;18:180–188
  24. Hachinski VC, Iliff LD, Zilkha E, DuBoulay GH, McAllister VL, Marshall J, et al. Cerebral blood flow in dementia. Archives of Neurology. 1975;32:632–637
  25. Hampel H, Teipel SJ, Alexander GE, Horwitz B, Teichberg D, Schapiro MB, et al. Corpus callosum atrophy is a possible indicator of region-and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Archives of Neurology. 1998;55:193–198
  26. Hampel H, Teipel SJ, Alexander GE, Pogarell O, Rapoport SI, Moller HJ. In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and PET. Journal of Neural Transmission. 2002;109:837–855
  27. Janowsky JS, Kaye JA, Carper RA. Atrophy of the corpus callosum in Alzheimer's disease versus healthy aging. Journal of the American Geriatrics Society. 1996;44:798–803
  28. Leys D, Pruvo JP, Parent M, Vermersch P, Soetaert G, Steinling M, et al. Could Wallerian degeneration contribute to “leuko-araoisis” in subjects free of any vascular disorder?. Journal of Neurology, Neurosurgery and Psychiatry. 1991;54:46–50
  29. Lyoo IK, Satlin A, Lee CK, Renshaw PF. Regional atrophy of the corpus callosum in subjects with Alzheimer's disease and multi-infarct dementia. Psychiatry Research. 1997;74:63–72
  30. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939–944
  31. Meguro K, Constans JM, Shimada M, Yamaguchi S, Ishizaki J, Ishii H, et al. Corpus callosum atrophy, white matter lesions, and frontal executive dysfunction in normal aging and Alzheimer's disease. A community-based study: the Tajiri Project. International Psychogeriatrics. 2003;15:9–25
  32. Monsh AU, Bondi MW, Butters N, Salmon DP, Katzman R, Thal LJ. Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type. Archives of Neurology. 1992;49:1253–1258
  33. Montgomery SA, Ǻsberg M. A new depression scale designed to be sensitive to change. British Journal of Psychiatry. 1979;134:382–389
  34. Pantel J, Schroder J, Jauss M, Essig M, Minakaran R, Schonknecht P, et al. Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer's disease. Psychiatry Research. 1999;90:181–192
  35. Rose SE, Chen F, Chalk JB, Zelaya FO, Strugnell WE, Benson M, et al. Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging. Journal of Neurology, Neurosurgery and Psychiatry. 2000;69:528–530
  36. Roth M, Tym E, Mountjoy CQ, Huppert FA, Hendrie H, Verma S, et al. CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. British Journal of Psychiatry. 1986;149:698–709
  37. Rüsch N, van Elst LT, Ludaescher P, Wilke M, Huppertz HJ, Thiel T, et al. A voxel-based morphometric MRI study in female patients with borderline personality disorder. NeuroImage. 2003;20:385–392
  38. Salat DH, Kaye JA, Janowsky JS. Prefrontal gray and white matter volumes in healthy aging and Alzheimer's disease. Archives of Neurology. 1999;56:338–344
  39. Sowell ER, Thompson PM, Holmes CJ, Batth R, Jernigan TL, Toga AW. Localizing age-related changes in brain structure between childhood and adolescence using statistical parametric mapping. NeuroImage. 1999;9:587–597
  40. Sugihara S, Kinoshita T, Matsusue E, Fujii S, Ogawa T. Usefulness of diffusion tensor imaging of white matter in Alzheimer disease and vascular dementia. Acta Radiologica. 2004;45:658–663
  41. Takahashi S, Yonezawa H, Takahashi J, Kudo M, Inoue T, Tohgi H. Selective reduction of diffusion anisotropy in white matter of Alzheimer disease brains measured by 3.0 Tesla magnetic resonance imaging. Neuroscience Letters. 2002;332:45–48
  42. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. New York: Thieme Medical Publishers, Inc.; 1988;
  43. Tanabe JL, Amend D, Schuff N, DiSclafani V, Ezekiel F, Norman D, et al. Tissue segmentation of the brain in Alzheimer disease. American Journal of Neuroradiology. 1997;18:115–123
  44. Teipel SJ, Bayer W, Alexander GE, Zebur Y, Teichberg D, Kulic L, et al. Progression of corpus callosum atrophy in Alzheimer disease. Archives of Neurology. 2002;59:243–248
  45. Teipel SJ, Bayer W, Alexander GE, Bokde AL, Zebuhr Y, Teichberg D, et al. Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration. Neurobiology of Aging. 2003;24:85–94
  46. Thompson PM, Moussai J, Zohoori S, Goldkorn A, Khan AA, Mega MS, et al. Cortical variability and asymmetry in normal aging and Alzheimer's disease. Cerebral Cortex. 1998;8:492–509
  47. Tomimoto H, Lin JX, Matsuo A, Ihara M, Ohtani R, Shibata M, et al. Different mechanisms of corpus callosum atrophy in Alzheimer's disease and vascular dementia. Journal of Neurology. 2004;251:398–406
  48. Wright IC, McGuire PK, Poline J-B, Travere JM, Murray RM, Frackowiak RSJ, et al. A voxel-based method for the statistical analysis of grey and white matter density applied to schizophrenia. NeuroImage. 1995;2:244–252

PII: S0925-4927(06)00063-1

doi: 10.1016/j.pscychresns.2006.04.003

Psychiatry Research: Neuroimaging
Volume 154, Issue 1 , Pages 59-68 , 15 January 2007

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