Psychiatry Research: Neuroimaging
Volume 146, Issue 3 , Pages 283-287 , 30 April 2006

Predicting conversion to dementia in mild cognitive impairment by volumetric and diffusivity measurements of the hippocampus

  • Andreas Fellgiebel

      Affiliations

    • Department of Psychiatry, University of Mainz, Untere Zahlbacher Str. 8, D-55131 Mainz, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 6131 172525; fax: +49 6131 176690.
    • ,
  • Paulo R. Dellani

      Affiliations

    • Institute of Neuroradiology, University of Mainz, Mainz, Germany
    • ,
  • Dirk Greverus

      Affiliations

    • Department of Psychiatry, University of Mainz, Untere Zahlbacher Str. 8, D-55131 Mainz, Germany
    • ,
  • Armin Scheurich

      Affiliations

    • Department of Psychiatry, University of Mainz, Untere Zahlbacher Str. 8, D-55131 Mainz, Germany
    • ,
  • Peter Stoeter

      Affiliations

    • Institute of Neuroradiology, University of Mainz, Mainz, Germany
    • ,
  • Matthias J. Müller

      Affiliations

    • Department of Psychiatry, University of Mainz, Untere Zahlbacher Str. 8, D-55131 Mainz, Germany

Received 16 November 2005 ,Revised 10 January 2006 ,Accepted 16 January 2006.

References 

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  2. Fellgiebel A, Wille P, Müller MJ, Winterer G, Scheurich A, Vucurevic G, et al. Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study. Dementia and Geriatric Cognitive Disorders. 2004;18:101–108
  3. Geslani DM, Tierney MC, Herrmann N, Szalai JP. Mild cognitive impairment: an operational definition and its conversion rate to Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 2005;19:383–389
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  8. Laakso MP, Frisoni GB, Kononen M, Mikkonen M, Beltramello A, Geroldi C, et al. Hippocampus and entorhinal cortex in frontotemporal dementia and Alzheimer's disease: a morphometric MRI study. Biological Psychiatry. 2000;47:1056–1063
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  10. Müller MJ, Greverus D, Dellani PR, Weibrich C, Wille PR, Scheurich A, et al. Functional implications of hippocampal volume and diffusivity in mild cognitive impairment. Neuroimage. 2005;28:1033–1042
  11. Müller MJ, Mazanek M, Weibrich C, Dellani PR, Stoeter P, Fellgiebel A. Distribution characteristics, reproducibility, and precision of region of interest-based hippocampal diffusion tensor imaging measures. American Journal of Neuroradiology. 2006;27:440–446
  12. Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hanninen T, Laakso MP, et al. Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiology of Aging. 2004;25:303–310
  13. Pennanen C, Testa C, Laakso MP, Hallikainen M, Helkala EL, Hanninen T, et al. A voxel based morphometry study on mild cognitive impairment. Journal of Neurology, Neurosurgery and Psychiatry. 2005;76:11–14
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PII: S0925-4927(06)00013-8

doi: 10.1016/j.pscychresns.2006.01.006

Psychiatry Research: Neuroimaging
Volume 146, Issue 3 , Pages 283-287 , 30 April 2006

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