Psychiatry Research: Neuroimaging
Volume 146, Issue 1 , Pages 87-90 , 30 January 2006

Striatal dopamine D2/D3 receptor availability in male smokers

  • Yen Kuang Yang

      Affiliations

    • Department of Psychiatry, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan 704, Taiwan
    • Corresponding Author InformationCorresponding author. Tel.: +886 6 2766188; fax: +886 6 2759259.
    • ,
  • Wei Jen Yao

      Affiliations

    • Department of Nuclear Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    • ,
  • Joseph P. McEvoy

      Affiliations

    • John Umstead Hospital, Butner, NC and Duke University Medical Center, Durham, NC, USA
    • ,
  • Ching Lin Chu

      Affiliations

    • Department of Psychiatry, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan 704, Taiwan
    • ,
  • I Hui Lee

      Affiliations

    • Department of Psychiatry, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan 704, Taiwan
    • ,
  • Po See Chen

      Affiliations

    • Department of Psychiatry, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan 704, Taiwan
    • ,
  • Tzung Lieh Yeh

      Affiliations

    • Department of Psychiatry, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan 704, Taiwan
    • ,
  • Nan Tsing Chiu

      Affiliations

    • Department of Nuclear Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Received 9 March 2005 ,Revised 22 May 2005 ,Accepted 29 September 2005.

References 

  1. Balfour DJ, Ridley DL. The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction?. Pharmacology, Biochemistry and Behavior. 2000;66:79–85
  2. Bierut LJ, Rice JP, Edenberg HJ, Goate A, Foroud T, Cloninger CR, et al. Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. American Journal of Medical Genetics. 2000;90:299–302
  3. Court JA, Lloyd S, Thomas N, Piggott MA, Marshall EF, Morris CM, et al. Dopamine and nicotinic receptor availability and the levels of dopamine and homovanillic acid in human brain related to tobacco use. Neuroscience. 1998;87:63–78
  4. Dagher A, Bleicher C, Aston JA, Gunn RN, Clarke PB, Cumming P. Reduced dopamine D1 receptor availability in the ventral striatum of cigarette smokers. Synapse. 2001;42:48–53
  5. Fowler JS, Volkow ND, Wang GJ, Pappas N, Logan J, MacGregor R, et al. Inhibition of monoamine oxidase B in the brains of smokers. Nature. 1996;379:733–736
  6. Guo JZ, Tredway TL, Chiappinelli VA. Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus. Journal of Neuroscience. 1998;18:1963–1969
  7. Hamajima N, Ito H, Matsuo K, Saito T, Tajima K, Ando M, et al. Association between smoking habits and dopamine receptor D2 taqI A A2 allele in Japanese males: a confirmatory study. Journal of Epidemiology. 2002;12:297–304
  8. Krause KH, Dresel SH, Krause J, Kung HF, Tatsch K, Ackenheil M. Stimulant-like action of nicotine on striatal dopamine transporter in the brain of adults with attention deficit hyperactivity disorder. International Journal of Neuropsychopharmacology. 2002;5:111–113
  9. Krause KH, Dresel SH, Krause J, la Fougere C, Ackenheil M. The dopamine transporter and neuroimaging in attention deficit hyperactivity disorder. Neuroscience and Biobehavioral Reviews. 2003;27:605–613
  10. Laruelle M. Imaging synaptic neurotransmission with in vivo availability competition techniques: a critical review. Journal of Cerebral Blood Flow and Metabolism. 2000;20:423–451
  11. Martin-Solch C, Magyar S, Kunig G, Missimer J, Schultz W, Leenders KL. Changes in brain activation associated with reward processing in smokers and nonsmokers. A positron emission tomography study. Experimental Brain Research. 2001;139:278–286
  12. Pich EM, Pagliusi SR, Tessari M, Talabot-Ayer D, Hooft van Huijsduijnen R, Chiamulera C. Common neural substrates for the addictive properties of nicotine and cocaine. Science. 1997;275:83–86
  13. Rose JE, Corrigall WA. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology. 1997;130:28–40
  14. Staley JK, Krishnan-Sarin S, Zoghbi S, Tamagnan G, Fujita M, Seibyl JP, et al. Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers. Synapse. 2001;41:275–284
  15. Vles JS, Feron FJ, Hendriksen JG, Jolles J, van Kroonenburgh MJ, Weber WE. Methylphenidate down-regulates the dopamine receptor and transporter system in children with attention deficit hyperkinetic disorder (ADHD). Neuropediatrics. 2003;34:77–80
  16. Watkins SS, Koob GF, Markou A. Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. Nicotine and Tobacco Research. 2000;2:19–37
  17. Wonnacott S. Presynaptic nicotinic ACh receptors. Trends in Neurosciences. 1997;20:92–98
  18. Yang YK, Nelson L, Kamaraju L, Wilson W, McEvoy JP. Nicotine decreases bradykinesia-rigidity in haloperidol-treated patients with schizophrenia. Neuropsychopharmacology. 2002;27:684–686
  19. Yang YK, Yeh TL, Chiu NT, Lee IH, Chen PS, Lee LC, et al. Association between cognitive performance and striatal dopamine availability is higher in timing and motor tasks in patients with schizophrenia. Psychiatry Research: Neuroimaging. 2004;131:209–216

PII: S0925-4927(05)00171-X

doi: 10.1016/j.pscychresns.2005.09.008

Psychiatry Research: Neuroimaging
Volume 146, Issue 1 , Pages 87-90 , 30 January 2006

Article Tools